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Dhrs11 Gene Detail
Summary
  • Symbol
    Dhrs11
  • Name
    dehydrogenase/reductase 11
  • Synonyms
    dehydrogenase/reductase (SDR family) member 11, MGC:18716
  • Feature Type
    protein coding gene
  • IDs
    MGI:2652816
    NCBI Gene: 192970
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:84711682-84719820 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    466 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2652816
 protein coding gene Chr11:84711547-84719880 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018872
 protein coding gene Chr11:86270029-86278160 (-)
A/J MGP_AJ_G0018839
 protein coding gene Chr11:82979337-82987464 (-)
AKR/J MGP_AKRJ_G0018809
 protein coding gene Chr11:85435716-85443829 (-)
BALB/cJ MGP_BALBcJ_G0018812
 protein coding gene Chr11:83368652-83376790 (-)
C3H/HeJ MGP_C3HHeJ_G0018626
 protein coding gene Chr11:85491663-85499794 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019264
 protein coding gene Chr11:88893561-88905277 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016897
 protein coding gene Chr11:80067322-80075516 (-)
CAST/EiJ MGP_CASTEiJ_G0018181
 protein coding gene Chr11:86127482-86135670 (-)
CBA/J MGP_CBAJ_G0018597
 protein coding gene Chr11:92660611-92672089 (-)
DBA/2J MGP_DBA2J_G0018705
 protein coding gene Chr11:82552381-82560585 (-)
FVB/NJ MGP_FVBNJ_G0018694
 protein coding gene Chr11:82045977-82054107 (-)
LP/J MGP_LPJ_G0018775
 protein coding gene Chr11:86796900-86805031 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018721
 protein coding gene Chr11:92808024-92816193 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019304
 protein coding gene Chr11:85712181-85720336 (-)
PWK/PhJ MGP_PWKPhJ_G0017950
 protein coding gene Chr11:83325823-83334117 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017742
 protein coding gene Chr11:85263085-85271814 (-)
WSB/EiJ MGP_WSBEiJ_G0018232
 protein coding gene Chr11:85555580-85563718 (-)



Homology
more
  • Human Ortholog
    DHRS11, dehydrogenase/reductase 11
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DHRS11, dehydrogenase/reductase 11
  • Synonyms
    ARPG836, SDR24C1, spDHRS11
  • Links
    NCBI Gene ID: 79154
    UniProt: Q6UWP2

  • Chr Location
    17q12; chr17:36591879-36600804 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    727
  • Tissues
    1
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034449 Ensembl Gene Model | MGI Sequence Detail 8139 C57BL/6J ±  kb
transcript ENSMUST00000047560 Ensembl | MGI Sequence Detail 1254 Not Applicable  
polypeptide ENSMUSP00000043467 Ensembl | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory