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Crygn Gene Detail
Summary
  • Symbol
    Crygn
  • Name
    crystallin, gamma N
  • Feature Type
    protein coding gene
  • IDs
    MGI:2449167
    NCBI Gene: 214301
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:24956000-24962846 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 11.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    273 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2449167
 protein coding gene Chr5:24956000-24963006 (-)
129S1/SvImJ ENSMUSG00200012832
 protein coding gene Chr5:20565595-20572621 (-)
A/J ENSMUSG00195038466
 protein coding gene Chr5:20034271-20041318 (-)
AKR/J ENSMUSG00220033912
 protein coding gene Chr5:20116912-20123957 (-)
BALB/cJ ENSMUSG00180019851
 protein coding gene Chr5:19900986-19907993 (-)
C3H/HeJ ENSMUSG00175046650
 protein coding gene Chr5:21832479-21839526 (-)
C57BL/6NJ ENSMUSG00215040332
 protein coding gene Chr5:20467936-20474942 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027023
 protein coding gene Chr5:19661930-19669096 (-)
CAST/EiJ ENSTCUG00005003025
 protein coding gene Chr5:20043419-20050285 (-)
CBA/J ENSMUSG00210044767
 protein coding gene Chr5:20871763-20878810 (-)
DBA/2J ENSMUSG00185035305
 protein coding gene Chr5:22411173-22418221 (-)
FVB/NJ ENSMUSG00205030242
 protein coding gene Chr5:19624021-19631031 (-)
JF1/MsJ ENSUMUG00000003763
 protein coding gene Chr5:26974028-26981074 (-)
LP/J ENSMUSG00230023316
 protein coding gene Chr5:26847566-26854588 (-)
NOD/ShiLtJ ENSMUSG00190004883
 protein coding gene Chr5:19939659-19946665 (-)
NZO/HlLtJ ENSMUSG00225016999
 protein coding gene Chr5:32263258-32270295 (-)
PWK/PhJ ENSLUMG00010032860
 protein coding gene Chr5:20010813-20017830 (-)
SPRET/EiJ ENSMSPG00010032673
 protein coding gene Chr5:20863843-20870468 (-)
WSB/EiJ ENSIUOG00005036363
 protein coding gene Chr5:22769656-22776701 (-)



Homology
more
  • Human Ortholog
    CRYGN, crystallin gamma N
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CRYGN, crystallin gamma N
  • Links
    NCBI Gene ID: 155051
    UniProt: Q8WXF5

  • Chr Location
    7q36.1; chr7:151428832-151440813 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a conditional allele activated in rhombomeres 3 and 5 derived neurons exhibit reduced MNTB volumne between P4 and P25 with increase in the amplitude of wave IV ABR.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    2
  • cDNA Data
    17
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 214301 NCBI Gene Model | MGI Sequence Detail 6847 C57BL/6J ±  kb
    transcript NM_153076 RefSeq | MGI Sequence Detail 609 C57BL/6  
    polypeptide Q8VHL5 UniProt | EBI | MGI Sequence Detail 183 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 17
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 2
      Phenotypes 19
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory