Vsig10 Gene Detail

Summary

• Symbol
  Vsig10
• Name
  V-set and immunoglobulin domain containing 10

• Feature Type
  protein coding gene
• IDs
  MGI:2448533
  NCBI Gene: 231668
• Alliance
  gene page
• Transcription Start Sites
  5 TSS

Location &
Maps

• Sequence Map
  Chr5:117457331-117493071 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 56.88 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  254 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2448533	protein coding gene	Chr5:117457148-117493071 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029986	protein coding gene	Chr5:120391357-120439540 (+)
A/J	MGP_AJ_G0029950	protein coding gene	Chr5:115502069-115538024 (+)
AKR/J	MGP_AKRJ_G0029889	protein coding gene	Chr5:119234599-119270669 (+)
BALB/cJ	MGP_BALBcJ_G0029961	protein coding gene	Chr5:116920018-116956543 (+)
C3H/HeJ	MGP_C3HHeJ_G0029681	protein coding gene	Chr5:119749307-119791626 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0030416	protein coding gene	Chr5:124977997-125020441 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027642	protein coding gene	Chr5:110264162-110299566 (+)
CAST/EiJ	MGP_CASTEiJ_G0029090	protein coding gene	Chr5:118757226-118795420 (+)
CBA/J	MGP_CBAJ_G0029649	protein coding gene	Chr5:129800142-129844069 (+)
DBA/2J	MGP_DBA2J_G0029799	protein coding gene	Chr5:115599120-115636592 (+)
FVB/NJ	MGP_FVBNJ_G0029755	protein coding gene	Chr5:114465508-114501639 (+)
LP/J	MGP_LPJ_G0029887	protein coding gene	Chr5:120897656-120935954 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029786	protein coding gene	Chr5:134026219-134063107 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030457	protein coding gene	Chr5:118756465-118795668 (+)
PWK/PhJ	MGP_PWKPhJ_G0028803	protein coding gene	Chr5:114288005-114329050 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028641	protein coding gene	Chr5:116315823-116361491 (+)
WSB/EiJ	MGP_WSBEiJ_G0029165	protein coding gene	Chr5:119327795-119367628 (+)

Homology

• Human Ortholog
  VSIG10, V-set and immunoglobulin domain containing 10

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  VSIG10, V-set and immunoglobulin domain containing 10
  
• Links
  HGNC:26078

  NCBI Gene ID: 54621

  neXtProt AC: NX_Q8N0Z9

  UniProt: Q8N0Z9

  
  
• Chr Location
  12q24.23; chr12:118063593-118104402 (-)  GRCh38.p7

---

• Alliance of Genome Resources
  Vsig10 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: VSIG10
• Gene Tree
  Vsig10
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  13 phenotype references
  

• All Mutations and Alleles
  16
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Gene trapped
  11
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  2 involving Vsig10
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  24 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  22

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase vsig10
  ZFIN vsig10

Interactions

• Vsig10 interacts with 229 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

Sequences &
Gene Models

• All Sequences
  40
• RefSeq
  2
• UniProt
  3
• CCDS
  CCDS19603.2

• Ensembl
  ENSMUSG00000066894 (Evidence)
• NCBI Gene
  231668

Representative Sequences			Length	Strain/Species
genomic	231668	NCBI Gene Model | MGI Sequence Detail	35741	C57BL/6J
transcript	NM_001033311	RefSeq | MGI Sequence Detail	4054	C57BL/6
polypeptide	D3YX43	UniProt | EBI | MGI Sequence Detail	558	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000029851 V-set and immunoglobulin domain-containing protein 10
  (term hierarchy)
• InterPro Domains
  IPR013098 Immunoglobulin I-set
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR003599 Immunoglobulin subtype
  IPR003598 Immunoglobulin subtype 2
  IPR013106 Immunoglobulin V-set domain

Molecular
Reagents

• All nucleic 22

  cDNA 22

  
  

  Microarray probesets 4

References

• Summaries
  All 30

  Gene Ontology 1

  Phenotypes 13
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Vsig10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr48376	Chr5:117456803-117456824 (+)	-517 bp
Tssr48377	Chr5:117457127-117457174 (+)	-180 bp
Tssr48378	Chr5:117457323-117457349 (+)	5 bp
Tssr48379	Chr5:117457357-117457391 (+)	43 bp
Tssr48380	Chr5:117457406-117457417 (+)	81 bp