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Pip5kl1 Gene Detail
Summary
  • Symbol
    Pip5kl1
  • Name
    phosphatidylinositol-4-phosphate 5-kinase-like 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448520
    NCBI Gene: 227733
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:32465238-32473799 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448520
 protein coding gene Chr2:32464809-32473799 (+)
129S1/SvImJ ENSMUSG00200052486
 protein coding gene Chr2:29437361-29446409 (+)
A/J ENSMUSG00195040193
 protein coding gene Chr2:29538756-29547801 (+)
AKR/J ENSMUSG00220052402
 protein coding gene Chr2:29656657-29665703 (+)
BALB/cJ ENSMUSG00180052982
 protein coding gene Chr2:29553406-29562456 (+)
C3H/HeJ ENSMUSG00175053590
 protein coding gene Chr2:29519837-29528885 (+)
C57BL/6NJ ENSMUSG00215046751
 protein coding gene Chr2:29585318-29594367 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023439
 protein coding gene Chr2:28442158-28451085 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210016407
 protein coding gene Chr2:29592370-29601419 (+)
DBA/2J ENSMUSG00185047998
 protein coding gene Chr2:29452018-29461063 (+)
FVB/NJ ENSMUSG00205026769
 protein coding gene Chr2:29298766-29307812 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230039709
 protein coding gene Chr2:31372676-31381724 (+)
NOD/ShiLtJ ENSMUSG00190051690
 protein coding gene Chr2:29553162-29562207 (+)
NZO/HlLtJ ENSMUSG00225007982
 protein coding gene Chr2:39125915-39134953 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PIP5KL1, phosphatidylinositol-4-phosphate 5-kinase like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIP5KL1, phosphatidylinositol-4-phosphate 5-kinase like 1
  • Synonyms
    PIPKH
  • Links
    NCBI Gene ID: 138429
    UniProt: Q5T9C9

  • Chr Location
    9q34.11; chr9:127920881-127930785 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    694
  • Tissues
    97
  • cDNA Data
    8
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 227733 NCBI Gene Model | MGI Sequence Detail 8562 C57BL/6J ±  kb
transcript NM_001379020 RefSeq | MGI Sequence Detail 1583 C57BL/6  
polypeptide Q6U7H8 UniProt | EBI | MGI Sequence Detail 395 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000012748 phosphatidylinositol 4-phosphate 5-kinase-like protein 1
    (term hierarchy)
  • InterPro Domains
    IPR023610 Phosphatidylinositol-4/5-phosphate 5/4-kinase
    IPR002498 Phosphatidylinositol-4-phosphate 4/5-kinase, core
    IPR027483 Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily
    IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
  • GlyGen
    Q6U7H8 1 site
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:307860 Choquet H, et al., A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory