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Sbno2 Gene Detail
Summary
  • Symbol
    Sbno2
  • Name
    strawberry notch 2
  • Synonyms
    Stno
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448490
    NCBI Gene: 216161
  • Alliance
    genome feature page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79892826-79941405 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    835 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448490
 protein coding gene Chr10:79892826-79941942 (-)
129S1/SvImJ ENSMUSG00200042948
 protein coding gene Chr10:76521540-76534933 (-)
129S1/SvImJ ENSMUSGG00200054977
 protein coding gene Chr10:76539460-76545939 (-)
A/J ENSMUSG00195040276
 protein coding gene Chr10:76917082-76930475 (-)
A/J ENSMUSGG00195055494
 protein coding gene Chr10:76935002-76941481 (-)
AKR/J ENSMUSGG00220054920
 protein coding gene Chr10:76532562-76539041 (-)
AKR/J ENSMUSG00220043413
 protein coding gene Chr10:76514642-76528035 (-)
BALB/cJ ENSMUSGG00180055592
 protein coding gene Chr10:76945489-76951968 (-)
BALB/cJ ENSMUSG00180048471
 protein coding gene Chr10:76927567-76940962 (-)
C3H/HeJ ENSMUSG00175052144
 protein coding gene Chr10:76798272-76811667 (-)
C3H/HeJ ENSMUSGG00175055181
 protein coding gene Chr10:76816194-76822673 (-)
C57BL/6NJ ENSMUSG00215050112
 protein coding gene Chr10:76539970-76553363 (-)
C57BL/6NJ ENSMUSGG00215055199
 protein coding gene Chr10:76557890-76564370 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015563
 protein coding gene Chr10:74043478-74088196 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210040692
 protein coding gene Chr10:76654347-76667741 (-)
CBA/J ENSMUSGG00210055120
 protein coding gene Chr10:76672268-76678747 (-)
DBA/2J ENSMUSG00185044171
 protein coding gene Chr10:76996734-77010126 (-)
DBA/2J ENSMUSGG00185057957
 protein coding gene Chr10:77014653-77021132 (-)
FVB/NJ ENSMUSG00205040331
 protein coding gene Chr10:76709521-76722915 (-)
FVB/NJ ENSMUSGG00205054670
 protein coding gene Chr10:76727442-76733922 (-)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055892
 protein coding gene Chr10:78784382-78790861 (-)
LP/J ENSMUSG00230046785
 protein coding gene Chr10:78766462-78779855 (-)
NOD/ShiLtJ ENSMUSGG00190055122
 protein coding gene Chr10:76928384-76934863 (-)
NOD/ShiLtJ ENSMUSG00190034382
 protein coding gene Chr10:76910466-76923857 (-)
NZO/HlLtJ ENSMUSG00225050726
 protein coding gene Chr10:83052817-83066210 (-)
NZO/HlLtJ ENSMUSGG00225055708
 protein coding gene Chr10:83070737-83077216 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SBNO2, strawberry notch homolog 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SBNO2, strawberry notch homolog 2
  • Synonyms
    KIAA0963, SNO, STNO
  • Links
    NCBI Gene ID: 22904
    UniProt: Q9Y2G9

  • Chr Location
    19p13.3; chr19:1107636-1174295 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 1 allele in 1 genetic background
    2 images
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit impaired osteoclast fusion, impaired osteoblastogenesis, osteopetrosis, increased bone mass, and decreased body weight.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    615
  • Tissues
    4
  • cDNA Data
    80
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035673 Ensembl Gene Model | MGI Sequence Detail 48580 C57BL/6J ±  kb
    transcript ENSMUST00000219260 Ensembl | MGI Sequence Detail 4850 Not Applicable  
    polypeptide ENSMUSP00000151590 Ensembl | MGI Sequence Detail 1349 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 80
      cDNA 80

      Microarray probesets 3
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 15
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory