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Enox1 Gene Detail
Summary
  • Symbol
    Enox1
  • Name
    ecto-NOX disulfide-thiol exchanger 1
  • Synonyms
    D230005D02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444896
    NCBI Gene: 239188
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:77394203-77959200 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 40.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5420 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444896
 protein coding gene Chr14:77393790-77959203 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021584
 protein coding gene Chr14:72135044-72732690 (+)
A/J MGP_AJ_G0021542
 protein coding gene Chr14:70440116-71005824 (+)
AKR/J MGP_AKRJ_G0021519
 protein coding gene Chr14:72534494-73113865 (+)
BALB/cJ MGP_BALBcJ_G0021549
 protein coding gene Chr14:70234110-70808206 (+)
C3H/HeJ MGP_C3HHeJ_G0021326
 protein coding gene Chr14:72249835-72823775 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021989
 protein coding gene Chr14:75254947-75851445 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019527
 protein coding gene Chr14:68028520-68579481 (+)
CAST/EiJ MGP_CASTEiJ_G0020843
 protein coding gene Chr14:68991699-69598372 (+)
CBA/J MGP_CBAJ_G0021294
 protein coding gene Chr14:77693319-78300351 (+)
DBA/2J MGP_DBA2J_G0021417
 protein coding gene Chr14:69827761-70391125 (+)
FVB/NJ MGP_FVBNJ_G0021395
 protein coding gene Chr14:69173899-69730205 (+)
LP/J MGP_LPJ_G0021487
 protein coding gene Chr14:73261131-73855073 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021422
 protein coding gene Chr14:76355419-76953281 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022012
 protein coding gene Chr14:71816033-72404077 (+)
PWK/PhJ MGP_PWKPhJ_G0020586
 protein coding gene Chr14:66610284-67169134 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020423
 protein coding gene Chr14:67784624-68369167 (+)
WSB/EiJ MGP_WSBEiJ_G0020896
 protein coding gene Chr14:72156961-72734726 (+)



Homology
more
  • Human Ortholog
    ENOX1, ecto-NOX disulfide-thiol exchanger 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ENOX1, ecto-NOX disulfide-thiol exchanger 1
  • Synonyms
    bA64J21.1, cCNOX, CNOX, PIG38
  • Links
    NCBI Gene ID: 55068
    neXtProt AC: NX_Q8TC92
    UniProt: Q8TC92

  • Chr Location
    13q14.11; chr13:43213130-43786972 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
DNA-templated transcription
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    814
  • Tissues
    34
  • cDNA Data
    9
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022012 Ensembl Gene Model | MGI Sequence Detail 564998 C57BL/6J ±  kb
    transcript ENSMUST00000227662 Ensembl | MGI Sequence Detail 3064 Not Applicable  
    polypeptide ENSMUSP00000154512 Ensembl | MGI Sequence Detail 662 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 17
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:326354 Allegre N, et al., NANOG initiates epiblast fate through the coordination of pluripotency genes expression. Nat Commun. 2022 Jun 21;13(1):3550
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/21/2023
    MGI 6.22     		The Jackson Laboratory