Zfp827 MGI Mouse Gene Detail - MGI:2444807

Symbol

Zfp827
Name

zinc finger protein 827
Synonyms

2810449M09Rik, D630040G17Rik

Feature Type

protein coding gene
IDs

MGI:2444807
NCBI Gene: 622675
Alliance

genome feature page
Transcription Start Sites

7 TSS

Sequence Map

Chr8:79755066-79920395 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 37.36 cM
Mapping Data

2 experiments

SNPs within 2kb

4399 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444807	protein coding gene	Chr8:79753754-79920397 (+)
129S1/SvImJ	ENSMUSG00200022518	protein coding gene	Chr8:74113713-74276390 (+)
A/J	ENSMUSG00195016320	protein coding gene	Chr8:74464785-74627458 (+)
AKR/J	ENSMUSG00220021138	protein coding gene	Chr8:74556572-74719267 (+)
BALB/cJ	ENSMUSG00180016439	protein coding gene	Chr8:74315881-74478554 (+)
C3H/HeJ	ENSMUSG00175010926	protein coding gene	Chr8:74395146-74557809 (+)
C57BL/6NJ	ENSMUSG00215013592	protein coding gene	Chr8:74031589-74194264 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031246	protein coding gene	Chr8:70588739-70753101 (+)
CAST/EiJ	ENSTCUG00005032290	protein coding gene	Chr8:73962890-74123639 (+)
CBA/J	no annotation
DBA/2J	ENSMUSG00185010937	protein coding gene	Chr8:80496333-80659021 (+)
FVB/NJ	ENSMUSG00205017264	protein coding gene	Chr8:73486984-73649706 (+)
JF1/MsJ	ENSUMUG00000010456	protein coding gene	Chr8:82838695-82998644 (+)
LP/J	ENSMUSG00230026115	protein coding gene	Chr8:84114694-84277352 (+)
NOD/ShiLtJ	ENSMUSG00190023266	protein coding gene	Chr8:74407011-74569288 (+)
NZO/HlLtJ	ENSMUSG00225023109	protein coding gene	Chr8:87493904-87656162 (+)
PWK/PhJ	ENSLUMG00010026302	protein coding gene	Chr8:74254949-74415146 (+)
SPRET/EiJ	ENSMSPG00010022723	protein coding gene	Chr8:75981526-76145344 (+)
WSB/EiJ	ENSIUOG00005015104	protein coding gene	Chr8:75164678-75333681 (+)

Human Ortholog

ZNF827, zinc finger protein 827

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF827, zinc finger protein 827
Links

HGNC:27193

NCBI Gene ID: 152485

UniProt: Q17R98
Chr Location

4q31.21-q31.22; chr4:145757627-145938823 (-) GRCh38

MGI Vertebrate Homology

Zfp827 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ZNF827
Gene Tree

Zfp827

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

23
Chemically induced (other)

1
Endonuclease-mediated

3
Gene trapped

19
Genomic Mutations

1 involving Zfp827
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

58 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

26
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

58

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

114
RefSeq

51
UniProt

7
CCDS

CCDS52604.1, CCDS80900.1

Ensembl

ENSMUSG00000071064 (Evidence)
NCBI Gene

622675

			Length	Strain/Species	Flank
genomic	ENSMUSG00000071064	Ensembl Gene Model \| MGI Sequence Detail	165330	C57BL/6J	± kb
transcript	ENSMUST00000238669	Ensembl \| MGI Sequence Detail	4511	Not Applicable
polypeptide	ENSMUSP00000158613	Ensembl \| MGI Sequence Detail	1346	Not Applicable

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UniProt

7 Sequences
Protein Ontology

PR:000018178 zinc finger protein 827

(term hierarchy)
InterPro Domains

IPR050688 Zinc finger and ubiquitin peptidase domain-containing protein

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type
GlyGen

Q505G8 1 site

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All nucleic 60

Genomic 2

cDNA 58

Microarray probesets 4

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MGI:1925647

Summaries

All 38

Gene Ontology 4

Phenotypes 11
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Zfp827:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr78123	Chr8:79754598-79754607 (+)	-463 bp
Tssr78124	Chr8:79754807-79754866 (+)	-229 bp
Tssr78125	Chr8:79754882-79754938 (+)	-156 bp
Tssr78126	Chr8:79754946-79754979 (+)	-103 bp
Tssr2612	Chr8:79754980-79754995 (+)	-78 bp
Tssr78127	Chr8:79755194-79755242 (+)	152 bp
Tssr78128	Chr8:79755258-79755283 (+)	205 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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