Tcp11l2 MGI Mouse Gene Detail - MGI:2444679 - t-complex 11 (mouse) like 2

Symbol

Tcp11l2
Name

t-complex 11 (mouse) like 2
Synonyms

E430026E19Rik

Feature Type

protein coding gene
IDs

MGI:2444679
NCBI Gene: 216198
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr10:84412811-84450219 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 41.55 cM
Mapping Data

2 experiments

SNPs within 2kb

490 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444679	protein coding gene	Chr10:84412490-84450223 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017592	protein coding gene	Chr10:85449441-85487198 (+)
A/J	MGP_AJ_G0017572	protein coding gene	Chr10:82549782-82588580 (+)
AKR/J	MGP_AKRJ_G0017531	protein coding gene	Chr10:84844642-84881717 (+)
BALB/cJ	MGP_BALBcJ_G0017535	protein coding gene	Chr10:82799698-82837642 (+)
C3H/HeJ	MGP_C3HHeJ_G0017357	protein coding gene	Chr10:84927471-84966835 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017992	protein coding gene	Chr10:88342437-88381978 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015676	protein coding gene	Chr10:78373521-78410987 (+)
CAST/EiJ	MGP_CASTEiJ_G0016924	protein coding gene	Chr10:84779015-84818823 (+)
CBA/J	MGP_CBAJ_G0017327	protein coding gene	Chr10:92053890-92094663 (+)
DBA/2J	MGP_DBA2J_G0017433	protein coding gene	Chr10:81693239-81731300 (+)
FVB/NJ	MGP_FVBNJ_G0017427	protein coding gene	Chr10:80928137-80966186 (+)
LP/J	MGP_LPJ_G0017505	protein coding gene	Chr10:86087446-86128247 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017455	protein coding gene	Chr10:93649984-93693485 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018029	protein coding gene	Chr10:84765632-84807499 (+)
PWK/PhJ	MGP_PWKPhJ_G0016705	protein coding gene	Chr10:81552686-81591586 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016494	protein coding gene	Chr10:83392575-83429827 (+)
WSB/EiJ	MGP_WSBEiJ_G0016983	protein coding gene	Chr10:84754994-84794132 (+)

Human Ortholog

TCP11L2, t-complex 11 like 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TCP11L2, t-complex 11 like 2
Links

HGNC:28627

NCBI Gene ID: 255394

neXtProt AC: NX_Q8N4U5

UniProt: Q8N4U5
Chr Location

12q23.3; chr12:106297935-106347003 (+) GRCh38

Alliance of Genome Resources

Tcp11l2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TCP11L2
Gene Tree

Tcp11l2

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Phenotype Summary

9 phenotype references

All Mutations and Alleles

5
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

1
Targeted

2
Genomic Mutations

1 involving Tcp11l2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

14 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

877
Tissues

18
cDNA Data

70
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tcp11l2

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Tcp11l2 interacts with 106 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

35
RefSeq

2
UniProt

1
CCDS

CCDS36016.1

Ensembl

ENSMUSG00000020034 (Evidence)
NCBI Gene

216198

			Length	Strain/Species	Flank
genomic	216198	NCBI Gene Model \| MGI Sequence Detail	37409	C57BL/6J	± kb
transcript	NM_146008	RefSeq \| MGI Sequence Detail	2400	C57BL/6
polypeptide	Q8K1H7	UniProt \| EBI \| MGI Sequence Detail	517	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000016203 T-complex protein 11-like protein 2

(term hierarchy)
InterPro Domains

IPR008862 T-complex 11

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All nucleic 70

cDNA 70

Microarray probesets 2

Summaries

All 28

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 9
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Tcp11l2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr94898	Chr10:84412747-84412768 (+)	-53 bp
Tssr94899	Chr10:84420515-84420526 (+)	7,710 bp
Tssr94900	Chr10:84420722-84420732 (+)	7,916 bp
Tssr3297	Chr10:84435391-84435394 (+)	22,582 bp
Tssr94901	Chr10:84444412-84444451 (+)	31,621 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/12/2023 MGI 6.22