About   Help   FAQ
Scara3 Gene Detail
Summary
  • Symbol
    Scara3
  • Name
    scavenger receptor class A, member 3
  • Synonyms
    C130058N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444418
    NCBI Gene: 219151
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:66156843-66191384 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 34.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1053 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444418
 protein coding gene Chr14:66156843-66191427 (-)
129S1/SvImJ ENSMUSG00200026551
 protein coding gene Chr14:54757355-54791905 (-)
A/J ENSMUSG00195012841
 protein coding gene Chr14:54934706-54969238 (-)
AKR/J ENSMUSG00220031773
 protein coding gene Chr14:54275201-54309737 (-)
BALB/cJ ENSMUSG00180030049
 protein coding gene Chr14:54550881-54585420 (-)
C3H/HeJ ENSMUSG00175032924
 protein coding gene Chr14:56293754-56328308 (-)
C57BL/6NJ ENSMUSG00215017869
 protein coding gene Chr14:54489803-54524341 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019431
 protein coding gene Chr14:57065034-57097893 (-)
CAST/EiJ ENSTCUG00005035947
 protein coding gene Chr14:56196461-56231007 (-)
CBA/J ENSMUSG00210033334
 protein coding gene Chr14:54922044-54956578 (-)
DBA/2J ENSMUSG00185031116
 protein coding gene Chr14:60091585-60126139 (-)
FVB/NJ ENSMUSG00205021694
 protein coding gene Chr14:54437519-54472054 (-)
JF1/MsJ ENSUMUG00000030563
 protein coding gene Chr14:71265489-71300333 (-)
LP/J ENSMUSG00230033269
 protein coding gene Chr14:72120873-72155427 (-)
NOD/ShiLtJ ENSMUSG00190028243
 protein coding gene Chr14:54716752-54751282 (-)
NZO/HlLtJ ENSMUSG00225039713
 protein coding gene Chr14:62449653-62484187 (-)
PWK/PhJ ENSLUMG00010034678
 protein coding gene Chr14:54156265-54191140 (-)
SPRET/EiJ ENSMSPG00010028221
 protein coding gene Chr14:57646908-57681542 (-)
WSB/EiJ ENSIUOG00005038990
 protein coding gene Chr14:54153410-54187943 (-)



Homology
more
  • Human Ortholog
    SCARA3, scavenger receptor class A member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCARA3, scavenger receptor class A member 3
  • Synonyms
    APC7, CSR, CSR1, MSLR1, MSRL1
  • Links
    NCBI Gene ID: 51435
    UniProt: Q6AZY7

  • Chr Location
    8p21.1; chr8:27633414-27734141 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    703
  • Tissues
    39
  • cDNA Data
    34
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034463 Ensembl Gene Model | MGI Sequence Detail 34542 C57BL/6J ±  kb
transcript ENSMUST00000042046 Ensembl | MGI Sequence Detail 3597 Not Applicable  
polypeptide ENSMUSP00000046525 Ensembl | MGI Sequence Detail 606 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014491 scavenger receptor class A member 3
    (term hierarchy)
  • InterPro Domains
    IPR008160 Collagen triple helix repeat
    IPR052376 Oxidative Scavengers and Glycosyltransferases
  • GlyGen
    Q8C850 11 sites, 6 N-linked glycans (9 sites)
Molecular
Reagents
less
  • All nucleic 36
    cDNA 34
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 40
    Developmental Gene Expression 10
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory