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Fcgbp Gene Detail
Summary
  • Symbol
    Fcgbp
  • Name
    Fc fragment of IgG binding protein
  • Synonyms
    A430096B05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444336
    NCBI Gene: 215384
  • Alliance
    gene page
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:27770661-27820287 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 16.26 cM
Strain
Comparison
more
  • SNPs within 2kb
    336 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444336
 protein coding gene Chr7:27770661-27820289 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031929
 protein coding gene Chr7:26828975-26877068 (+)
A/J MGP_AJ_G0031908
 protein coding gene Chr7:26161735-26218876 (+)
AKR/J MGP_AKRJ_G0031839
 protein coding gene Chr7:26847438-26902564 (+)
BALB/cJ MGP_BALBcJ_G0031914
 protein coding gene Chr7:26336283-26382876 (+)
C3H/HeJ MGP_C3HHeJ_G0031636
 protein coding gene Chr7:27209014-27258306 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032379
 protein coding gene Chr7:27683755-27744882 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029431
 protein coding gene Chr7:27298602-27336396 (+)
CAST/EiJ MGP_CASTEiJ_G0030971
 protein coding gene Chr7:20536126-20576001 (+)
CBA/J MGP_CBAJ_G0031599
 protein coding gene Chr7:28914685-28976150 (+)
DBA/2J MGP_DBA2J_G0031752
 protein coding gene Chr7:25945069-25997433 (+)
FVB/NJ MGP_FVBNJ_G0031709
 protein coding gene Chr7:26033844-26071325 (+)
LP/J MGP_LPJ_G0031833
 protein coding gene Chr7:27144900-27199371 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031744
 protein coding gene Chr7:28449369-28509181 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032409
 protein coding gene Chr7:26314195-26366029 (+)
PWK/PhJ MGP_PWKPhJ_G0030694
 protein coding gene Chr7:20955800-21002530 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030529
 protein coding gene Chr7:17332455-17343693 (+)
WSB/EiJ MGP_WSBEiJ_G0031078
 protein coding gene Chr7:26666570-26709842 (+)



Homology
more
  • Human Ortholog
    FCGBP, Fc gamma binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FCGBP, Fc gamma binding protein
  • Synonyms
    FC(GAMMA)BP
  • Links
    NCBI Gene ID: 8857
    neXtProt AC: NX_Q9Y6R7
    UniProt: Q9Y6R7

  • Chr Location
    19q13.2; chr19:39863323-39934626 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    10
  • cDNA Data
    231
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047730 Ensembl Gene Model | MGI Sequence Detail 49627 C57BL/6J ±  kb
    transcript ENSMUST00000138392 Ensembl | MGI Sequence Detail 7926 Not Applicable  
    polypeptide ENSMUSP00000114271 Ensembl | MGI Sequence Detail 2583 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      12 Sequences
    • InterPro Domains
      IPR003645 Follistatin-like, N-terminal
      IPR036084 Serine protease inhibitor-like superfamily
      IPR036773 TGF-beta binding (TB) domain superfamily
      IPR025615 TILa domain
      IPR002919 Trypsin Inhibitor-like, cysteine rich domain
      IPR001846 von Willebrand factor, type D domain
      IPR001007 VWFC domain
      IPR014853 VWF/SSPO/Zonadhesin-like, cysteine-rich domain
    Molecular
    Reagents
    less
    • All nucleic 231
      cDNA 231

      Microarray probesets 3
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:307299 Ehrencrona E, et al., The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds. J Biol Chem. 2021 Jun 11;297(1):100871
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/19/2023
    MGI 6.22     		The Jackson Laboratory