Svopl Gene Detail

Summary

• Symbol
  Svopl
• Name
  SV2 related protein homolog (rat)-like
• Synonyms
  9430071P14Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2444335
  NCBI Gene: 320590
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr6:37960674-38023931 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 17.34 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  2030 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444335	protein coding gene	Chr6:37960674-38023944 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0030579	protein coding gene	Chr6:36249101-36315237 (-)
A/J	MGP_AJ_G0030552	protein coding gene	Chr6:34687146-34752792 (-)
AKR/J	MGP_AKRJ_G0030479	protein coding gene	Chr6:35792461-35859501 (-)
BALB/cJ	MGP_BALBcJ_G0030562	protein coding gene	Chr6:34879006-34942500 (-)
C3H/HeJ	MGP_C3HHeJ_G0030275	protein coding gene	Chr6:35798393-35863808 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0031016	protein coding gene	Chr6:37168773-37232941 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028228	protein coding gene	Chr6:32602572-32667565 (-)
CAST/EiJ	MGP_CASTEiJ_G0029677	protein coding gene	Chr6:35682245-35752797 (-)
CBA/J	MGP_CBAJ_G0030253	protein coding gene	Chr6:38592755-38658959 (-)
DBA/2J	MGP_DBA2J_G0030397	protein coding gene	Chr6:34508646-34573005 (-)
FVB/NJ	MGP_FVBNJ_G0030351	protein coding gene	Chr6:34297858-34361167 (-)
LP/J	MGP_LPJ_G0030484	protein coding gene	Chr6:36311081-36375090 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0030387	protein coding gene	Chr6:40978395-41041940 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031046	protein coding gene	Chr6:35710354-35776205 (-)
PWK/PhJ	MGP_PWKPhJ_G0029391	protein coding gene	Chr6:34151770-34220620 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0029227	protein coding gene	Chr6:35431165-35501167 (-)
WSB/EiJ	MGP_WSBEiJ_G0029753	protein coding gene	Chr6:35657067-35721514 (-)

Homology

• Human Ortholog
  SVOPL, SVOP like

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  SVOPL, SVOP like
  
• Synonyms
  SLC22B5
• Links
  HGNC:27034

  NCBI Gene ID: 136306

  UniProt: Q8N434

  
  
• Chr Location
  7q34; chr7:138594285-138701362 (-)  GRCh38

---

• MGI Vertebrate Homology
  Svopl stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: SVOPL
• Gene Tree
  Svopl
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  4
• Endonuclease-mediated
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  21 strains or lines available

Expression

• Assay Results
  788
• Tissues
  56
• cDNA Data
  10
• Literature Summary
  6

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase svopl
  ZFIN svopl

Sequences &
Gene Models

• All Sequences
  42
• RefSeq
  6
• UniProt
  2
• CCDS
  CCDS20009.2

• Ensembl
  ENSMUSG00000029830 (Evidence)
• NCBI Gene
  320590

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000029830	Ensembl Gene Model | MGI Sequence Detail	63258	C57BL/6J
transcript	ENSMUST00000096040	Ensembl | MGI Sequence Detail	2366	Not Applicable
polypeptide	ENSMUSP00000093743	Ensembl | MGI Sequence Detail	494	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000032740 putative transporter SVOPL
  (term hierarchy)
• InterPro Domains
  IPR005828 Major facilitator, sugar transporter-like
  IPR020846 Major facilitator superfamily domain
  IPR036259 MFS transporter superfamily
• GlyGen
  Q6PDF3 1 site

Molecular
Reagents

• All nucleic 11

  cDNA 10

  Primer pair 1

  
  

  Microarray probesets 2

References

• Summaries
  All 27

  Developmental Gene Expression 6

  Phenotypes 5
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Svopl:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr60365	Chr6:38023929-38023933 (-)	0 bp
Tssr60364	Chr6:38000216-38000227 (-)	23,709 bp
Tssr60363	Chr6:37979933-37979935 (-)	43,997 bp