Fam169a MGI Mouse Gene Detail - MGI:2444268 - family with sequence similarity 169, member A

Symbol

Fam169a
Name

family with sequence similarity 169, member A
Synonyms

B230112C05Rik

Feature Type

protein coding gene
IDs

MGI:2444268
NCBI Gene: 320557
Alliance

gene page
Transcription Start Sites

12 TSS

Sequence Map

Chr13:97203795-97266801 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 50.66 cM
Mapping Data

2 experiments

SNPs within 2kb

500 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444268	protein coding gene	Chr13:97203794-97267521 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020856	protein coding gene	Chr13:98645078-98726361 (+)
A/J	MGP_AJ_G0020810	protein coding gene	Chr13:94924689-94991335 (+)
AKR/J	MGP_AKRJ_G0020784	protein coding gene	Chr13:97810460-97883146 (+)
BALB/cJ	MGP_BALBcJ_G0020807	protein coding gene	Chr13:95611816-95675975 (+)
C3H/HeJ	MGP_C3HHeJ_G0020600	protein coding gene	Chr13:97542230-97608992 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021242	protein coding gene	Chr13:101622317-101703498 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018812	protein coding gene	Chr13:90691914-90754784 (+)
CAST/EiJ	MGP_CASTEiJ_G0020118	protein coding gene	Chr13:96850208-96919253 (+)
CBA/J	MGP_CBAJ_G0020559	protein coding gene	Chr13:105686610-105762926 (+)
DBA/2J	MGP_DBA2J_G0020684	protein coding gene	Chr13:94678503-94743127 (+)
FVB/NJ	MGP_FVBNJ_G0020665	protein coding gene	Chr13:93447603-93511979 (+)
LP/J	MGP_LPJ_G0020759	protein coding gene	Chr13:98764397-98834407 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020693	protein coding gene	Chr13:106027875-106108608 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021283	protein coding gene	Chr13:97235557-97307062 (+)
PWK/PhJ	MGP_PWKPhJ_G0019870	protein coding gene	Chr13:93461937-93524309 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019694	protein coding gene	Chr13:93528492-93587099 (+)
WSB/EiJ	MGP_WSBEiJ_G0020175	protein coding gene	Chr13:97696867-97761624 (+)

Human Ortholog

FAM169A, family with sequence similarity 169 member A

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM169A, family with sequence similarity 169 member A
Synonyms

SLAP75
Links

HGNC:29138

NCBI Gene ID: 26049

neXtProt AC: NX_Q9Y6X4

UniProt: Q9Y6X4
Chr Location

5q13.3; chr5:74777574-74867994 (-) GRCh38.p7

Alliance of Genome Resources

Fam169a stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: FAM169A
Gene Tree

Fam169a

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

451
Endonuclease-mediated

1
Gene trapped

448
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

238 strains or lines available

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

714
Tissues

3
cDNA Data

53
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase fam169a

ZFIN fam169aa

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Fam169a interacts with 339 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

60
RefSeq

20
UniProt

1
CCDS

CCDS49337.1

Ensembl

ENSMUSG00000041817 (Evidence)
NCBI Gene

320557

			Length	Strain/Species	Flank
genomic	320557	NCBI Gene Model \| MGI Sequence Detail	63007	C57BL/6J	± kb
transcript	NM_001100458	RefSeq \| MGI Sequence Detail	4570	C57BL/6
polypeptide	Q5XG69	UniProt \| EBI \| MGI Sequence Detail	665	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000032364 soluble lamin-associated protein of 75 kDa

(term hierarchy)
InterPro Domains

IPR029625 Protein FAM169

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All nucleic 54

cDNA 54

Microarray probesets 4

Summaries

All 29

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 8
Earliest

J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Fam169a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr120749	Chr13:97202112-97202119 (+)	-1,679 bp
Tssr120750	Chr13:97203774-97203789 (+)	-13 bp
Tssr120751	Chr13:97207796-97207825 (+)	4,016 bp
Tssr120752	Chr13:97207839-97207864 (+)	4,057 bp
Tssr120753	Chr13:97207916-97207932 (+)	4,129 bp
Tssr120754	Chr13:97207942-97207955 (+)	4,154 bp
Tssr120755	Chr13:97208071-97208134 (+)	4,308 bp
Tssr120756	Chr13:97208135-97208145 (+)	4,345 bp
Tssr120757	Chr13:97210071-97210078 (+)	6,280 bp
Tssr120758	Chr13:97224991-97224997 (+)	21,199 bp
Tssr120759	Chr13:97225052-97225090 (+)	21,276 bp
Tssr120760	Chr13:97265163-97265181 (+)	61,377 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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