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Ankrd54 Gene Detail
Summary
  • Symbol
    Ankrd54
  • Name
    ankyrin repeat domain 54
  • Synonyms
    C730048E16Rik, Liar
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444209
    NCBI Gene: 223690
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:78937294-78947093 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    314 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444209
 protein coding gene Chr15:78937294-78947129 (-)
129S1/SvImJ ENSMUSG00200048759
 protein coding gene Chr15:76050514-76060298 (-)
A/J ENSMUSG00195048213
 protein coding gene Chr15:75992195-76001987 (-)
AKR/J ENSMUSG00220051430
 protein coding gene Chr15:76035604-76045394 (-)
BALB/cJ ENSMUSG00180047475
 protein coding gene Chr15:75869190-75878981 (-)
C3H/HeJ ENSMUSG00175047163
 protein coding gene Chr15:76180468-76190259 (-)
C57BL/6NJ ENSMUSG00215051667
 protein coding gene Chr15:75947611-75957402 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020002
 protein coding gene Chr15:73049906-73060603 (-)
CAST/EiJ ENSTCUG00005046629
 protein coding gene Chr15:75492171-75501985 (-)
CBA/J ENSMUSG00210046771
 protein coding gene Chr15:75955585-75965376 (-)
DBA/2J ENSMUSG00185039844
 protein coding gene Chr15:75965481-75975272 (-)
FVB/NJ ENSMUSG00205047758
 protein coding gene Chr15:75685307-75695098 (-)
JF1/MsJ ENSUMUG00000048425
 protein coding gene Chr15:75542694-75552571 (-)
LP/J ENSMUSG00230051605
 protein coding gene Chr15:79298946-79308730 (-)
NOD/ShiLtJ ENSMUSG00190033099
 protein coding gene Chr15:75976400-75986184 (-)
NZO/HlLtJ ENSMUSG00225053321
 protein coding gene Chr15:79627161-79636952 (-)
PWK/PhJ ENSLUMG00010051601
 protein coding gene Chr15:75762706-75772552 (-)
SPRET/EiJ ENSMSPG00010048873
 protein coding gene Chr15:77428599-77438416 (-)
WSB/EiJ ENSIUOG00005049034
 protein coding gene Chr15:76031432-76041223 (-)



Homology
more
  • Human Ortholog
    ANKRD54, ankyrin repeat domain 54
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD54, ankyrin repeat domain 54
  • Synonyms
    LIAR
  • Links
    NCBI Gene ID: 129138
    UniProt: Q6NXT1

  • Chr Location
    22q13.1; chr22:37830853-37849341 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    657
  • Tissues
    46
  • cDNA Data
    66
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033055 Ensembl Gene Model | MGI Sequence Detail 9800 C57BL/6J ±  kb
transcript ENSMUST00000040676 Ensembl | MGI Sequence Detail 1904 Not Applicable  
polypeptide ENSMUSP00000047042 Ensembl | MGI Sequence Detail 299 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 68

    Microarray probesets 4
Other
Accession IDs
less
MGI:1349386, MGI:1349445
References
more
  • Summaries
    All 54
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 3
    Phenotypes 26
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory