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Zcchc2 Gene Detail
Summary
  • Symbol
    Zcchc2
  • Name
    zinc finger, CCHC domain containing 2
  • Synonyms
    9930114B20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444114
    NCBI Gene: 227449
  • Alliance
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:105918136-105961804 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 49.76 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1174 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444114
protein coding gene Chr1:105916929-105961807 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016369
protein coding gene Chr1:108131798-108176010 (+)
A/J MGP_AJ_G0016353
protein coding gene Chr1:104349336-104392992 (+)
AKR/J MGP_AKRJ_G0016313
protein coding gene Chr1:107214719-107258389 (+)
BALB/cJ MGP_BALBcJ_G0016309
protein coding gene Chr1:104446808-104490465 (+)
C3H/HeJ MGP_C3HHeJ_G0016136
protein coding gene Chr1:107654073-107698452 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016768
protein coding gene Chr1:112279137-112324254 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014486
protein coding gene Chr1:98690291-98735108 (+)
CAST/EiJ MGP_CASTEiJ_G0015718
protein coding gene Chr1:106569777-106615095 (+)
CBA/J MGP_CBAJ_G0016109
protein coding gene Chr1:116109402-116155656 (+)
DBA/2J MGP_DBA2J_G0016214
protein coding gene Chr1:103418891-103462563 (+)
FVB/NJ MGP_FVBNJ_G0016215
protein coding gene Chr1:102357900-102401550 (+)
LP/J MGP_LPJ_G0016288
protein coding gene Chr1:109388665-109432322 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016241
protein coding gene Chr1:120554928-120598583 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016807
protein coding gene Chr1:107295606-107339266 (+)
PWK/PhJ MGP_PWKPhJ_G0015505
protein coding gene Chr1:102453708-102497484 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015290
protein coding gene Chr1:105961428-106005997 (+)
WSB/EiJ MGP_WSBEiJ_G0015781
protein coding gene Chr1:107132862-107176533 (+)



Homology
more
  • Human Ortholog
    ZCCHC2, zinc finger CCHC-type containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZCCHC2, zinc finger CCHC-type containing 2
  • Synonyms
    C18orf49
  • Links
    NCBI Gene ID: 54877
    neXtProt AC: NX_Q9C0B9
    UniProt: Q9C0B9

  • Chr Location
    18q21.33; chr18:62523025-62587709 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038866 Ensembl Gene Model | MGI Sequence Detail 43669 C57BL/6J ±  kb
    transcript ENSMUST00000118196 Ensembl | MGI Sequence Detail 5796 Not Applicable  
    polypeptide ENSMUSP00000113974 Ensembl | MGI Sequence Detail 1166 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2138574
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 14
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    06/12/2024
    MGI 6.13
    The Jackson Laboratory