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Dmxl1 Gene Detail
Summary
  • Symbol
    Dmxl1
  • Name
    Dmx-like 1
  • Synonyms
    C630007L23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443926
    NCBI Gene: 240283
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:49965737-50098540 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 27.12 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2607 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443926
 protein coding gene Chr18:49965657-50098540 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024419
 protein coding gene Chr18:48836056-48977424 (+)
A/J MGP_AJ_G0024385
 protein coding gene Chr18:46991552-47124290 (+)
AKR/J MGP_AKRJ_G0024355
 protein coding gene Chr18:48294562-48430708 (+)
BALB/cJ MGP_BALBcJ_G0024385
 protein coding gene Chr18:47117664-47250887 (+)
C3H/HeJ MGP_C3HHeJ_G0024152
 protein coding gene Chr18:48418796-48561787 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024831
 protein coding gene Chr18:50480087-50621929 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022264
 protein coding gene Chr18:46697963-46828898 (+)
CAST/EiJ MGP_CASTEiJ_G0023627
 protein coding gene Chr18:48402198-48542451 (+)
CBA/J MGP_CBAJ_G0024122
 protein coding gene Chr18:51923502-52086635 (+)
DBA/2J MGP_DBA2J_G0024252
 protein coding gene Chr18:46623548-46760689 (+)
FVB/NJ MGP_FVBNJ_G0024219
 protein coding gene Chr18:46186264-46319670 (+)
LP/J MGP_LPJ_G0024337
 protein coding gene Chr18:48845911-48993570 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024249
 protein coding gene Chr18:53449377-53619069 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024878
 protein coding gene Chr18:48258948-48397371 (+)
PWK/PhJ MGP_PWKPhJ_G0023370
 protein coding gene Chr18:46757828-46894490 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023176
 protein coding gene Chr18:48480200-48612174 (+)
WSB/EiJ MGP_WSBEiJ_G0023690
 protein coding gene Chr18:48142794-48280500 (+)



Homology
more
  • Human Ortholog
    DMXL1, Dmx like 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DMXL1, Dmx like 1
  • Links
    NCBI Gene ID: 1657
    UniProt: Q9Y485

  • Chr Location
    5q23.1; chr5:119037772-119249138 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    54
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037416 Ensembl Gene Model | MGI Sequence Detail 132804 C57BL/6J ±  kb
transcript ENSMUST00000041772 Ensembl | MGI Sequence Detail 12247 Not Applicable  
polypeptide ENSMUSP00000045559 Ensembl | MGI Sequence Detail 3025 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:359768 Eaton AF, et al., Dmxl1 Is an Essential Mammalian Gene that Is Required for V-ATPase Assembly and Function In Vivo. Function (Oxf). 2024 Jul 11;5(4)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory