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Phf21b Gene Detail
Summary
  • Symbol
    Phf21b
  • Name
    PHD finger protein 21B
  • Synonyms
    A730032D07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443812
    NCBI Gene: 271305
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:84669582-84740250 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 40.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2094 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443812
 protein coding gene Chr15:84669577-84740330 (-)
129S1/SvImJ ENSMUSG00200035638
 protein coding gene Chr15:81790115-81860672 (-)
A/J ENSMUSG00195016326
 protein coding gene Chr15:81716453-81787006 (-)
AKR/J ENSMUSG00220025730
 protein coding gene Chr15:81770367-81841024 (-)
BALB/cJ ENSMUSG00180015010
 protein coding gene Chr15:81593236-81663797 (-)
C3H/HeJ ENSMUSG00175026730
 protein coding gene Chr15:81904129-81974669 (-)
C57BL/6NJ ENSMUSG00215023742
 protein coding gene Chr15:81688395-81759074 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020117
 protein coding gene Chr15:78783240-78855295 (-)
CAST/EiJ ENSTCUG00005029391
 protein coding gene Chr15:81190680-81258769 (-)
CBA/J ENSMUSG00210013059
 protein coding gene Chr15:81679037-81749584 (-)
DBA/2J ENSMUSG00185021376
 protein coding gene Chr15:81715512-81786487 (-)
FVB/NJ ENSMUSG00205021075
 protein coding gene Chr15:81465876-81536526 (-)
JF1/MsJ ENSUMUG00000017593
 protein coding gene Chr15:81243959-81312660 (-)
LP/J ENSMUSG00230043745
 protein coding gene Chr15:85030364-85100909 (-)
NOD/ShiLtJ ENSMUSG00190023795
 protein coding gene Chr15:81703273-81773921 (-)
NZO/HlLtJ ENSMUSG00225048576
 protein coding gene Chr15:85369582-85440282 (-)
PWK/PhJ ENSLUMG00010031878
 protein coding gene Chr15:81452288-81520972 (-)
SPRET/EiJ ENSMSPG00010012612
 protein coding gene Chr15:83094081-83166074 (-)
WSB/EiJ ENSIUOG00005010141
 protein coding gene Chr15:81780287-81851002 (-)



Homology
more
  • Human Ortholog
    PHF21B, PHD finger protein 21B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHF21B, PHD finger protein 21B
  • Synonyms
    BHC80L, PHF4
  • Links
    NCBI Gene ID: 112885
    UniProt: Q96EK2

  • Chr Location
    22q13.31; chr22:44881162-45010022 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    29 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice exhibited impaired social memory and impaired long-term potentiation.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    79
  • cDNA Data
    22
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000016624 Ensembl Gene Model | MGI Sequence Detail 70669 C57BL/6J ±  kb
    transcript ENSMUST00000159939 Ensembl | MGI Sequence Detail 3639 Not Applicable  
    polypeptide ENSMUSP00000125355 Ensembl | MGI Sequence Detail 487 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 22
      Primer pair 2
      Antibodies 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 7
      Diseases 1
      Phenotypes 29
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory