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Akap17b Gene Detail
Summary
  • Symbol
    Akap17b
  • Name
    A kinase anchor protein 17B
  • Synonyms
    B230333C21Rik, C230056F04Rik, Sfrs17b, Srsf17b, Talia
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443758
    NCBI Gene: 338351
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:35871967-35909048 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 21.01 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    63 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443758
 protein coding gene ChrX:35871826-35909117 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035622
 protein coding gene ChrX:31523670-31562118 (-)
A/J MGP_AJ_G0035599
 protein coding gene ChrX:31602664-31639877 (-)
AKR/J MGP_AKRJ_G0035532
 protein coding gene ChrX:32283636-32337979 (-)
BALB/cJ MGP_BALBcJ_G0035592
 protein coding gene ChrX:31338078-31375316 (-)
C3H/HeJ MGP_C3HHeJ_G0035310
 protein coding gene ChrX:31837256-31876059 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036128
 protein coding gene ChrX:32158116-32192225 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032990
 protein coding gene ChrX:29837815-29876913 (-)
CAST/EiJ MGP_CASTEiJ_G0034601
 protein coding gene ChrX:20000373-20040211 (-)
CBA/J MGP_CBAJ_G0035279
 protein coding gene ChrX:33021173-33059066 (-)
DBA/2J MGP_DBA2J_G0035431
 protein coding gene ChrX:31432868-31470446 (-)
FVB/NJ MGP_FVBNJ_G0035377
 protein coding gene ChrX:31196748-31235700 (-)
LP/J MGP_LPJ_G0035513
 protein coding gene ChrX:31883000-31921174 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035421
 protein coding gene ChrX:33474773-33513680 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036135
 protein coding gene ChrX:31505297-31542373 (-)
PWK/PhJ MGP_PWKPhJ_G0034302
 protein coding gene ChrX:19477348-19514796 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034143
 protein coding gene ChrX:20492150-20531875 (-)
WSB/EiJ MGP_WSBEiJ_G0034736
 protein coding gene ChrX:31297875-31336748 (-)



Homology
more
  • Human Ortholog
    AKAP17A, A-kinase anchoring protein 17A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AKAP17A, A-kinase anchoring protein 17A
  • Synonyms
    721P, AKAP-17A, CCDC133, CXYorf3, DXYS155E, PRKA17A, SFRS17A, XE7, XE7Y
  • Links
    NCBI Gene ID: 8227
    neXtProt AC: NX_Q02040
    UniProt: Q02040

  • Chr Location
    XY;Y
  • Human Ortholog
    AKAP17BP, A-kinase anchoring protein 17B, pseudogene
  • Synonyms
    AKAP16B, AKAP16BP
  • Links
    NCBI Gene ID: 139516

  • Chr Location
    Xq24; chrX:119246541-119257673 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    8 images
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male chimeras hemizygous for a gene trapped allele are developmentally delayed and display failure of chorioallantoic fusion, a posterior truncation, neural tube defects, and impaired somite development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    15
  • cDNA Data
    31
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000059708 Ensembl Gene Model | MGI Sequence Detail 37082 C57BL/6J ±  kb
    transcript ENSMUST00000051906 Ensembl | MGI Sequence Detail 6003 Not Applicable  
    polypeptide ENSMUSP00000052042 Ensembl | MGI Sequence Detail 959 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 31
      Primer pair 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2147817
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory