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Senp5 Gene Detail
Summary
  • Symbol
    Senp5
  • Name
    SUMO/sentrin specific peptidase 5
  • Synonyms
    6230429P13Rik, A730063F07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443596
    NCBI Gene: 320213
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:31778490-31822105 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 22.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1167 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443596
 protein coding gene Chr16:31778488-31829388 (-)
129S1/SvImJ ENSMUSG00200034985
 protein coding gene Chr16:28798945-28842567 (-)
A/J ENSMUSG00195027926
 protein coding gene Chr16:28349621-28393233 (-)
AKR/J ENSMUSG00220030105
 protein coding gene Chr16:28638280-28679321 (-)
BALB/cJ ENSMUSG00180029780
 protein coding gene Chr16:28565450-28609069 (-)
C3H/HeJ ENSMUSG00175036871
 protein coding gene Chr16:28705456-28749396 (-)
C57BL/6NJ ENSMUSG00215012056
 protein coding gene Chr16:28583684-28627308 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020660
 protein coding gene Chr16:28962109-28999477 (-)
CAST/EiJ ENSTCUG00005034128
 protein coding gene Chr16:28974798-29018760 (-)
CBA/J ENSMUSG00210030396
 protein coding gene Chr16:28747470-28791412 (-)
DBA/2J ENSMUSG00185019029
 protein coding gene Chr16:28662937-28706881 (-)
FVB/NJ ENSMUSG00205017043
 protein coding gene Chr16:28681165-28724784 (-)
JF1/MsJ ENSUMUG00000018695
 protein coding gene Chr16:28840930-28881806 (-)
LP/J ENSMUSG00230027713
 protein coding gene Chr16:31231727-31275667 (-)
NOD/ShiLtJ ENSMUSG00190025467
 protein coding gene Chr16:28856768-28900379 (-)
NZO/HlLtJ ENSMUSG00225038614
 protein coding gene Chr16:34469223-34512836 (-)
PWK/PhJ ENSLUMG00010030784
 protein coding gene Chr16:28668569-28709848 (-)
SPRET/EiJ ENSMSPG00010017354
 protein coding gene Chr16:28660638-28700227 (-)
WSB/EiJ ENSIUOG00005031822
 protein coding gene Chr16:28836396-28880151 (-)



Homology
more
  • Human Ortholog
    SENP5, SUMO specific peptidase 5
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SENP5, SUMO specific peptidase 5
  • Links
    NCBI Gene ID: 205564
    UniProt: Q96HI0

  • Chr Location
    3q29; chr3:196867856-196934718 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    697
  • Tissues
    32
  • cDNA Data
    94
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022772 Ensembl Gene Model | MGI Sequence Detail 43616 C57BL/6J ±  kb
transcript ENSMUST00000231360 Ensembl | MGI Sequence Detail 6332 Not Applicable  
polypeptide ENSMUSP00000156109 Ensembl | MGI Sequence Detail 749 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 99
    cDNA 95
    Primer pair 4
    Antibodies 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923384, MGI:2146508, MGI:2146691
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory