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Slc16a5 Gene Detail
Summary
  • Symbol
    Slc16a5
  • Name
    solute carrier family 16 (monocarboxylic acid transporters), member 5
  • Synonyms
    A130015N09Rik, MCT5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443515
    NCBI Gene: 217316
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:115353300-115365224 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 80.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443515
 protein coding gene Chr11:115353231-115365224 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019388
 protein coding gene Chr11:119485937-119500266 (+)
A/J MGP_AJ_G0019357
 protein coding gene Chr11:114270515-114282937 (+)
AKR/J MGP_AKRJ_G0019327
 protein coding gene Chr11:117677175-117688971 (+)
BALB/cJ MGP_BALBcJ_G0019331
 protein coding gene Chr11:114684031-114703530 (+)
C3H/HeJ MGP_C3HHeJ_G0019137
 protein coding gene Chr11:118028130-118041314 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019781
 protein coding gene Chr11:123127173-123142670 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017404
 protein coding gene Chr11:111308527-111320457 (+)
CAST/EiJ MGP_CASTEiJ_G0018692
 protein coding gene Chr11:119344366-119357195 (+)
CBA/J MGP_CBAJ_G0019109
 protein coding gene Chr11:127979488-127993128 (+)
DBA/2J MGP_DBA2J_G0019220
 protein coding gene Chr11:113704039-113718423 (+)
FVB/NJ MGP_FVBNJ_G0019212
 protein coding gene Chr11:113183335-113198853 (+)
LP/J MGP_LPJ_G0019290
 protein coding gene Chr11:119870366-119884440 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019245
 protein coding gene Chr11:127155037-127169161 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019819
 protein coding gene Chr11:118333746-118346403 (+)
PWK/PhJ MGP_PWKPhJ_G0018456
 protein coding gene Chr11:114989387-115001940 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018249
 protein coding gene Chr11:118090940-118102955 (+)
WSB/EiJ MGP_WSBEiJ_G0018744
 protein coding gene Chr11:118280963-118295860 (+)



Homology
more
  • Human Ortholog
    SLC16A5, solute carrier family 16 member 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC16A5, solute carrier family 16 member 5
  • Synonyms
    MCT5, MCT6
  • Links
    NCBI Gene ID: 9121
    neXtProt AC: NX_O15375
    UniProt: O15375

  • Chr Location
    17q25.1; chr17:75087385-75110149 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    25
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045775 Ensembl Gene Model | MGI Sequence Detail 11925 C57BL/6J ±  kb
transcript ENSMUST00000092445 Ensembl | MGI Sequence Detail 1538 Not Applicable  
polypeptide ENSMUSP00000090102 Ensembl | MGI Sequence Detail 468 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    Genomic 2
    cDNA 25

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:293663 Jones RS, et al., Characterization and Proteomic-Transcriptomic Investigation of Monocarboxylate Transporter 6 Knockout Mice: Evidence of a Potential Role in Glucose and Lipid Metabolism. Mol Pharmacol. 2019 Sep;96(3):364-376
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory