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Marchf10 Gene Detail
Summary
  • Symbol
    Marchf10
  • Name
    membrane associated ring-CH-type finger 10
  • Synonyms
    4933417C16Rik, March10, OTTMUSG00000002847, Rnf190
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443469
    NCBI Gene: 632687
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:105251624-105347561 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 68.73 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2440 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443469
 protein coding gene Chr11:105251624-105348527 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019285
 protein coding gene Chr11:108596036-108689575 (-)
A/J MGP_AJ_G0019253
 protein coding gene Chr11:103961679-104050919 (-)
AKR/J MGP_AKRJ_G0019222
 protein coding gene Chr11:107097835-107191819 (-)
BALB/cJ MGP_BALBcJ_G0019227
 protein coding gene Chr11:104382662-104472762 (-)
C3H/HeJ MGP_C3HHeJ_G0019036
 protein coding gene Chr11:107391299-107482445 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019677
 protein coding gene Chr11:111963289-112062385 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017302
 protein coding gene Chr11:101298247-101393062 (-)
CAST/EiJ MGP_CASTEiJ_G0018589
 protein coding gene Chr11:108434657-108534627 (-)
CBA/J MGP_CBAJ_G0019005
 protein coding gene Chr11:116601365-116706514 (-)
DBA/2J MGP_DBA2J_G0019117
 protein coding gene Chr11:103452293-103543529 (-)
FVB/NJ MGP_FVBNJ_G0019108
 protein coding gene Chr11:102969167-103059126 (-)
LP/J MGP_LPJ_G0019187
 protein coding gene Chr11:109065390-109157782 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019138
 protein coding gene Chr11:115874536-115970987 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019714
 protein coding gene Chr11:107573984-107666263 (-)
PWK/PhJ MGP_PWKPhJ_G0018354
 protein coding gene Chr11:104545762-104643332 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018145
 protein coding gene Chr11:107330001-107428584 (-)
WSB/EiJ MGP_WSBEiJ_G0018640
 protein coding gene Chr11:107545490-107640181 (-)



Homology
more
  • Human Ortholog
    MARCHF10, membrane associated ring-CH-type finger 10
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MARCHF10, membrane associated ring-CH-type finger 10
  • Synonyms
    MARCH10, MARCH-X, RNF190
  • Links
    NCBI Gene ID: 162333
    UniProt: Q8NA82

  • Chr Location
    17q23.2; chr17:62701314-62808344 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    26
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078627 Ensembl Gene Model | MGI Sequence Detail 95938 C57BL/6J ±  kb
transcript ENSMUST00000049995 Ensembl | MGI Sequence Detail 3074 Not Applicable  
polypeptide ENSMUSP00000063198 Ensembl | MGI Sequence Detail 788 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • EC
    2.3.2.27
  • InterPro Domains
    IPR052297 RING-CH-type E3 ubiquitin-protein ligase
    IPR011016 Zinc finger, RING-CH-type
    IPR013083 Zinc finger, RING/FYVE/PHD-type
  • GlyGen
    E9PX79 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144453, MGI:3713496, MGI:6368848
References
more
  • Summaries
    All 23
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory