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Rps6kc1 Gene Detail
Summary
  • Symbol
    Rps6kc1
  • Name
    ribosomal protein S6 kinase polypeptide 1
  • Synonyms
    B130003F20Rik, RPK118
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443419
    NCBI Gene: 320119
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:190505076-190645207 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 96.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3440 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443419
protein coding gene Chr1:190432399-190645207 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016932
protein coding gene Chr1:197697164-197921581 (-)
A/J MGP_AJ_G0016911
protein coding gene Chr1:189600543-189815009 (-)
AKR/J MGP_AKRJ_G0016876
protein coding gene Chr1:195208838-195426012 (-)
BALB/cJ MGP_BALBcJ_G0016869
protein coding gene Chr1:190277699-190490443 (-)
C3H/HeJ MGP_C3HHeJ_G0016693
protein coding gene Chr1:196063164-196282350 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017332
protein coding gene Chr1:204009204-204231133 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015039
protein coding gene Chr1:180501853-180721397 (-)
CAST/EiJ MGP_CASTEiJ_G0016276
protein coding gene Chr1:195638839-195871845 (-)
CBA/J MGP_CBAJ_G0016667
protein coding gene Chr1:211561074-211792531 (-)
DBA/2J MGP_DBA2J_G0016773
protein coding gene Chr1:188325660-188537938 (-)
FVB/NJ MGP_FVBNJ_G0016769
protein coding gene Chr1:186449969-186663377 (-)
LP/J MGP_LPJ_G0016848
protein coding gene Chr1:198872195-199097549 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016801
protein coding gene Chr1:218277090-218509537 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017369
protein coding gene Chr1:195100453-195313903 (-)
PWK/PhJ MGP_PWKPhJ_G0016063
protein coding gene Chr1:187598166-187813653 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015839
protein coding gene Chr1:194076879-194302902 (-)
WSB/EiJ MGP_WSBEiJ_G0016338
protein coding gene Chr1:195307684-195536229 (-)



Homology
more
  • Human Ortholog
    RPS6KC1, ribosomal protein S6 kinase C1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPS6KC1, ribosomal protein S6 kinase C1
  • Synonyms
    humS6PKh1, RPK118, RSKL1, S6K-delta-1, S6PKh1
  • Links
    NCBI Gene ID: 26750
    neXtProt AC: NX_Q96S38
    UniProt: Q96S38

  • Chr Location
    1q32.3; chr1:213051233-213862735 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320119 NCBI Gene Model | MGI Sequence Detail 140132 C57BL/6J ±  kb
    transcript NM_178775 RefSeq | MGI Sequence Detail 4034 C57BL/6  
    polypeptide Q8BLK9 UniProt | EBI | MGI Sequence Detail 1056 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 60

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2138127, MGI:2138695
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 11
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    09/24/2024
    MGI 6.24
    The Jackson Laboratory