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Tmem131l Gene Detail
Summary
  • Symbol
    Tmem131l
  • Name
    transmembrane 131 like
  • Synonyms
    D930015E06Rik, mKIAA0922
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443399
    NCBI Gene: 229473
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:83804962-83947482 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 37.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5660 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443399
 protein coding gene Chr3:83804955-83947497 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027338
 protein coding gene Chr3:83781863-83936413 (-)
A/J MGP_AJ_G0027302
 protein coding gene Chr3:81012674-81154978 (-)
AKR/J MGP_AKRJ_G0027268
 protein coding gene Chr3:82912090-83060841 (-)
BALB/cJ MGP_BALBcJ_G0027311
 protein coding gene Chr3:81081395-81223143 (-)
C3H/HeJ MGP_C3HHeJ_G0027055
 protein coding gene Chr3:83229258-83376781 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027757
 protein coding gene Chr3:86910035-87063175 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025110
 protein coding gene Chr3:76691477-76834278 (-)
CAST/EiJ MGP_CASTEiJ_G0026502
 protein coding gene Chr3:83398498-83553960 (-)
CBA/J MGP_CBAJ_G0027030
 protein coding gene Chr3:89847070-90003586 (-)
DBA/2J MGP_DBA2J_G0027166
 protein coding gene Chr3:80529737-80673679 (-)
FVB/NJ MGP_FVBNJ_G0027134
 protein coding gene Chr3:78817170-78963177 (-)
LP/J MGP_LPJ_G0027274
 protein coding gene Chr3:84756770-84911496 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027153
 protein coding gene Chr3:96214141-96363917 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027815
 protein coding gene Chr3:82718561-82866953 (-)
PWK/PhJ MGP_PWKPhJ_G0026236
 protein coding gene Chr3:80298479-80444053 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026052
 protein coding gene Chr3:81896489-82047299 (-)
WSB/EiJ MGP_WSBEiJ_G0026580
 protein coding gene Chr3:83067395-83220151 (-)



Homology
more
  • Human Ortholog
    TMEM131L, transmembrane 131 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM131L, transmembrane 131 like
  • Synonyms
    KIAA0922
  • Links
    NCBI Gene ID: 23240
    UniProt: A2VDJ0

  • Chr Location
    4q31.3; chr4:153466346-153636711 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    920
  • Tissues
    143
  • cDNA Data
    207
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033767 Ensembl Gene Model | MGI Sequence Detail 142521 C57BL/6J ±  kb
transcript ENSMUST00000191758 Ensembl | MGI Sequence Detail 5555 Not Applicable  
polypeptide ENSMUSP00000141438 Ensembl | MGI Sequence Detail 1597 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000059682 transmembrane protein 131-like
    (term hierarchy)
  • InterPro Domains
    IPR013783 Immunoglobulin-like fold
    IPR039877 Transmembrane protein 131-like
    IPR045695 Transmembrane protein 131-like, conserved domain
    IPR022113 Transmembrane protein 131-like, N-terminal
  • GlyGen
    Q3U3D7 5 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 209
    cDNA 207
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:5897414
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory