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Fbxw21 Gene Detail
Summary
  • Symbol
    Fbxw21
  • Name
    F-box and WD-40 domain protein 21
  • Synonyms
    E330009P21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443323
    NCBI Gene: 320082
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr9:108968522-108991090 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    15 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443323
protein coding gene Chr9:108968515-108991109 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035328
protein coding gene Chr9:111115918-111144248 (-)
A/J MGP_AJ_G0035307
protein coding gene Chr9:107017592-107055632 (-)
AKR/J MGP_AKRJ_G0035239
protein coding gene Chr9:109715781-109745186 (-)
BALB/cJ MGP_BALBcJ_G0035301
protein coding gene Chr9:106718449-106745214 (-)
C3H/HeJ MGP_C3HHeJ_G0035011
protein coding gene Chr9:110103918-110131113 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035821
protein coding gene Chr9:114132772-114153757 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0034322
protein coding gene Chr9:110077960-110102153 (-)
CBA/J MGP_CBAJ_G0034979
protein coding gene Chr9:118164014-118199338 (-)
DBA/2J MGP_DBA2J_G0035140
protein coding gene Chr9:106475957-106515338 (-)
FVB/NJ MGP_FVBNJ_G0035088
protein coding gene Chr9:105303263-105322515 (-)
LP/J MGP_LPJ_G0035216
protein coding gene Chr9:111290516-111318036 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035127
protein coding gene Chr9:119727244-120060040 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035842
protein coding gene Chr9:109979462-110000086 (-)
PWK/PhJ MGP_PWKPhJ_G0034029
protein coding gene Chr9:106821637-107123833 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033864
protein coding gene Chr9:110060834-110657109 (-)
WSB/EiJ MGP_WSBEiJ_G0034443
protein coding gene Chr9:109881645-109904407 (-)



Homology
more
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Synonyms
    FBW12, FBXO12, FBXO35
  • Links
    NCBI Gene ID: 285231
    neXtProt AC: NX_Q6X9E4
    UniProt: Q6X9E4

  • Chr Location
    3p21.31; chr3:48372219-48401259 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 320082 NCBI Gene Model | MGI Sequence Detail 22569 C57BL/6J ±  kb
transcript NM_001382229 RefSeq | MGI Sequence Detail 2240 C57BL/6  
polypeptide NP_796043 RefSeq | MGI Sequence Detail 468 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001810 F-box domain
    IPR036047 F-box-like domain superfamily
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory