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Agbl2 Gene Detail
Summary
  • Symbol
    Agbl2
  • Name
    ATP/GTP binding protein-like 2
  • Synonyms
    A430081C19Rik, Ccp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443254
    NCBI Gene: 271813
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:90613071-90664781 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 50.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1249 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443254
 protein coding gene Chr2:90613029-90664781 (+)
129S1/SvImJ ENSMUSG00200051740
 protein coding gene Chr2:87528599-87580316 (+)
A/J ENSMUSG00195048912
 protein coding gene Chr2:87654006-87705736 (+)
AKR/J ENSMUSG00220047115
 protein coding gene Chr2:87458286-87510004 (+)
BALB/cJ ENSMUSG00180054784
 protein coding gene Chr2:87554195-87605927 (+)
C3H/HeJ ENSMUSG00175053949
 protein coding gene Chr2:87824291-87875997 (+)
C57BL/6NJ ENSMUSG00215053531
 protein coding gene Chr2:87655689-87707406 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023943
 protein coding gene Chr2:84910808-84958103 (+)
CAST/EiJ ENSTCUG00005051097
 protein coding gene Chr2:87066001-87117707 (+)
CBA/J ENSMUSG00210039003
 protein coding gene Chr2:87835459-87887185 (+)
DBA/2J ENSMUSG00185055977
 protein coding gene Chr2:87550658-87602394 (+)
FVB/NJ ENSMUSG00205050177
 protein coding gene Chr2:86848495-86900217 (+)
JF1/MsJ ENSUMUG00000011682
 protein coding gene Chr2:87370535-87422114 (+)
LP/J ENSMUSG00230036205
 protein coding gene Chr2:89301369-89353094 (+)
NOD/ShiLtJ ENSMUSG00190046317
 protein coding gene Chr2:87629419-87681146 (+)
NZO/HlLtJ ENSMUSG00225049420
 protein coding gene Chr2:97217730-97274672 (+)
PWK/PhJ ENSLUMG00010046355
 protein coding gene Chr2:87359379-87410841 (+)
SPRET/EiJ ENSMSPG00010051963
 protein coding gene Chr2:89323179-89356863 (+)
WSB/EiJ ENSIUOG00005053287
 protein coding gene Chr2:87357302-87408998 (+)



Homology
more
  • Human Ortholog
    AGBL2, AGBL carboxypeptidase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AGBL2, AGBL carboxypeptidase 2
  • Synonyms
    CCP2
  • Links
    NCBI Gene ID: 79841
    UniProt: Q5U5Z8

  • Chr Location
    11p11.2; chr11:47659591-47715389 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    23 phenotype references
Homozygous mice for a targeted allele are viable and fertile. Mice exhibit normal response to herpes simplex virus (HSV) and vaccinia virus (VACV) infection.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    611
  • Tissues
    14
  • cDNA Data
    13
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040812 Ensembl Gene Model | MGI Sequence Detail 51711 C57BL/6J ±  kb
transcript ENSMUST00000037219 Ensembl | MGI Sequence Detail 3462 Not Applicable  
polypeptide ENSMUSP00000048647 Ensembl | MGI Sequence Detail 862 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 13
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 49
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 23
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:373442 Zhou Y, et al., Loss-of-function variants in ciliary genes confer high risk for tetralogy of Fallot. Sci Adv. 2025 Oct 10;11(41):eadt0836
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory