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Clvs2 Gene Detail
Summary
  • Symbol
    Clvs2
  • Name
    clavesin 2
  • Synonyms
    A330019N05Rik, Rlbp1l2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443223
    NCBI Gene: 215890
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:33388282-33500680 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 18.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2961 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443223
 protein coding gene Chr10:33388282-33500765 (-)
129S1/SvImJ ENSMUSG00200007823
 protein coding gene Chr10:30310613-30345353 (-)
A/J ENSMUSG00195015427
 protein coding gene Chr10:30586733-30621488 (-)
AKR/J ENSMUSG00220010764
 protein coding gene Chr10:30273349-30308098 (-)
BALB/cJ ENSMUSG00180016358
 protein coding gene Chr10:30706760-30741514 (-)
C3H/HeJ ENSMUSG00175011432
 protein coding gene Chr10:30461727-30496479 (-)
C57BL/6NJ ENSMUSG00215009208
 protein coding gene Chr10:30249938-30284690 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015221
 protein coding gene Chr10:29317233-29418774 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210025217
 protein coding gene Chr10:30389158-30423910 (-)
DBA/2J ENSMUSG00185006767
 protein coding gene Chr10:30541987-30576739 (-)
FVB/NJ no annotation
JF1/MsJ no annotation
LP/J ENSMUSG00230015243
 protein coding gene Chr10:32307537-32342285 (-)
NOD/ShiLtJ ENSMUSG00190015007
 protein coding gene Chr10:30654998-30689755 (-)
NZO/HlLtJ ENSMUSG00225033466
 protein coding gene Chr10:36565919-36600671 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CLVS2, clavesin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLVS2, clavesin 2
  • Synonyms
    bA160A10.4, C6orf212, C6orf213, RLBP1L2
  • Links
    NCBI Gene ID: 134829
    UniProt: Q5SYC1

  • Chr Location
    6q22.31; chr6:122996131-123072925 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 215890 NCBI Gene Model | MGI Sequence Detail 112399 C57BL/6J ±  kb
transcript NM_175448 RefSeq | MGI Sequence Detail 2632 C57BL/6  
polypeptide Q8BG92 UniProt | EBI | MGI Sequence Detail 327 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:279375 Fritz KR, et al., Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract. Dev Dyn. 2019 Sep;248(9):795-812
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory