Tmem132c Gene Detail

Summary

• Symbol
  Tmem132c
• Name
  transmembrane protein 132C
• Synonyms
  2810482M11Rik, 4632425D07Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2443061
  NCBI Gene: 208213
• Alliance
  gene page
• Transcription Start Sites
  8 TSS

Location &
Maps

• Sequence Map
  Chr5:127318890-127642854 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 65.40 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  2713 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2443061	protein coding gene	Chr5:127318872-127642857 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0030115	protein coding gene	Chr5:131178343-131519105 (+)
A/J	MGP_AJ_G0030082	protein coding gene	Chr5:125691256-126009038 (+)
AKR/J	MGP_AKRJ_G0030016	protein coding gene	Chr5:129765864-130098077 (+)
BALB/cJ	MGP_BALBcJ_G0030092	protein coding gene	Chr5:127027827-127349862 (+)
C3H/HeJ	MGP_C3HHeJ_G0029809	protein coding gene	Chr5:130354712-130686349 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0030545	protein coding gene	Chr5:136229032-136571602 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027770	protein coding gene	Chr5:120138412-120460064 (+)
CAST/EiJ	MGP_CASTEiJ_G0029218	protein coding gene	Chr5:129552200-129886298 (+)
CBA/J	MGP_CBAJ_G0029779	protein coding gene	Chr5:141560438-141931510 (+)
DBA/2J	MGP_DBA2J_G0029929	protein coding gene	Chr5:125680410-126007033 (+)
FVB/NJ	MGP_FVBNJ_G0029885	protein coding gene	Chr5:124738469-125056942 (+)
LP/J	MGP_LPJ_G0030018	protein coding gene	Chr5:131704069-132042368 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029916	protein coding gene	Chr5:145015876-145362206 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030586	protein coding gene	Chr5:129416518-129758184 (+)
PWK/PhJ	MGP_PWKPhJ_G0028932	protein coding gene	Chr5:124554894-124872737 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028769	protein coding gene	Chr5:126986155-127307603 (+)
WSB/EiJ	MGP_WSBEiJ_G0029292	protein coding gene	Chr5:130080519-130424768 (+)

Homology

• Human Ortholog
  TMEM132C, transmembrane protein 132C

• Vertebrate Orthologs
  5

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TMEM132C, transmembrane protein 132C
  
• Synonyms
  PPP1R152
• Links
  HGNC:25436

  NCBI Gene ID: 92293

  neXtProt AC: NX_Q8N3T6

  UniProt: Q8N3T6

  
  
• Chr Location
  12q24.32-q24.33; chr12:128267170-128707911 (+)  GRCh38

---

• MGI Vertebrate Homology
  Tmem132c stringent orthology
  1 human;1 mouse;1 rat;3 zebrafish
  
• HCOP
  vertebrate homology predictions: TMEM132C
• Gene Tree
  Tmem132c
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Endonuclease-mediated
  2
• Gene trapped
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving Tmem132c
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  40 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  861
• Tissues
  40
• cDNA Data
  42
• Literature Summary
  3

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  39
• RefSeq
  2
• UniProt
  3
• CCDS
  CCDS51650.1

• Ensembl
  ENSMUSG00000034324 (Evidence)
• NCBI Gene
  208213

Representative Sequences			Length	Strain/Species
genomic	208213	NCBI Gene Model | MGI Sequence Detail	323965	C57BL/6J
transcript	NM_175432	RefSeq | MGI Sequence Detail	5113	C57BL/6
polypeptide	Q8CEF9	UniProt | EBI | MGI Sequence Detail	1099	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000030344 transmembrane protein 132C
  (term hierarchy)
• InterPro Domains
  IPR026307 Transmembrane protein 132
  IPR031437 Transmembrane protein family 132, middle domain
  IPR031436 Transmembrane protein TMEM132, C-terminal
  IPR031435 Transmembrane protein TMEM132, N-terminal

Molecular
Reagents

• All nucleic 45

  Genomic 1

  cDNA 42

  Primer pair 1

  Other 1

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:1920088

References

• Summaries
  All 33

  Developmental Gene Expression 3

  Gene Ontology 2

  Phenotypes 10
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Tmem132c:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr48959	Chr5:127318849-127318862 (+)	-34 bp
Tssr48960	Chr5:127318871-127318913 (+)	2 bp
Tssr48961	Chr5:127322210-127322217 (+)	3,324 bp
Tssr48962	Chr5:127334228-127334230 (+)	15,339 bp
Tssr48963	Chr5:127379671-127379675 (+)	60,783 bp
Tssr48964	Chr5:127483723-127483725 (+)	164,834 bp
Tssr48965	Chr5:127631785-127631796 (+)	312,901 bp
Tssr48966	Chr5:127641359-127641363 (+)	322,471 bp