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Fam161b Gene Detail
Summary
  • Symbol
    Fam161b
  • Name
    family with sequence similarity 161, member B
  • Synonyms
    9830169C18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443027
    NCBI Gene: 217705
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:84392083-84408607 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 39.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443027
protein coding gene Chr12:84392083-84408633 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019933
protein coding gene Chr12:85048950-85065474 (-)
A/J MGP_AJ_G0019890
protein coding gene Chr12:81828994-81845516 (-)
AKR/J MGP_AKRJ_G0019866
protein coding gene Chr12:84046601-84063879 (-)
BALB/cJ MGP_BALBcJ_G0019870
protein coding gene Chr12:82162655-82179179 (-)
C3H/HeJ MGP_C3HHeJ_G0019676
protein coding gene Chr12:84510751-84527275 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020321
protein coding gene Chr12:87489849-87510547 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017939
protein coding gene Chr12:78732199-78748132 (-)
CAST/EiJ MGP_CASTEiJ_G0019225
protein coding gene Chr12:79461781-79480328 (-)
CBA/J MGP_CBAJ_G0019647
protein coding gene Chr12:90873509-90891921 (-)
DBA/2J MGP_DBA2J_G0019762
protein coding gene Chr12:81358090-81374614 (-)
FVB/NJ MGP_FVBNJ_G0019748
protein coding gene Chr12:80309697-80326221 (-)
LP/J MGP_LPJ_G0019834
protein coding gene Chr12:84926746-84943645 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019787
protein coding gene Chr12:93785206-93803068 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020355
protein coding gene Chr12:83641179-83657574 (-)
PWK/PhJ MGP_PWKPhJ_G0018989
protein coding gene Chr12:75845254-75862163 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018784
protein coding gene Chr12:78130254-78146331 (-)
WSB/EiJ MGP_WSBEiJ_G0019277
protein coding gene Chr12:84352302-84368800 (-)



Homology
more
  • Human Ortholog
    FAM161B, FAM161 centrosomal protein B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM161B, FAM161 centrosomal protein B
  • Synonyms
    c14_5547, C14orf44
  • Links
    NCBI Gene ID: 145483
    neXtProt AC: NX_Q96MY7
    UniProt: Q96MY7

  • Chr Location
    14q24.3; chr14:73922699-73950414 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021234 Ensembl Gene Model | MGI Sequence Detail 16525 C57BL/6J ±  kb
    transcript ENSMUST00000065536 Ensembl | MGI Sequence Detail 3000 Not Applicable  
    polypeptide ENSMUSP00000070407 Ensembl | MGI Sequence Detail 589 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 2
    References
    more
    • Summaries
      All 29
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    06/12/2024
    MGI 6.13
    The Jackson Laboratory