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Fcrl1 Gene Detail
Summary
  • Symbol
    Fcrl1
  • Name
    Fc receptor-like 1
  • Synonyms
    A230020G22Rik, BXMAS1-like, Fcrh1, IFGP1, mBXMH1, mIFGP1, moFcRH1, moFcRH1L, moFcRH1S
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442862
    NCBI Gene: 229499
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:87283694-87310241 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 38.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    814 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442862
protein coding gene Chr3:87283656-87311274 (+)
129S1/SvImJ ENSMUSG00200036977
protein coding gene Chr3:84130478-84156898 (+)
A/J ENSMUSG00195051277
protein coding gene Chr3:84152996-84179425 (+)
AKR/J ENSMUSG00220045084
protein coding gene Chr3:84106578-84133013 (+)
BALB/cJ ENSMUSG00180046418
protein coding gene Chr3:84276179-84302614 (+)
C3H/HeJ ENSMUSG00175039291
protein coding gene Chr3:84080788-84107215 (+)
C57BL/6NJ ENSMUSG00215049590
protein coding gene Chr3:84526062-84552608 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025134
protein coding gene Chr3:80143627-80169258 (+)
CAST/EiJ ENSTCUG00005041695
protein coding gene Chr3:83602191-83628622 (+)
CBA/J ENSMUSG00210046225
protein coding gene Chr3:84223791-84250215 (+)
DBA/2J ENSMUSG00185052722
protein coding gene Chr3:84364925-84391359 (+)
FVB/NJ ENSMUSG00205035028
protein coding gene Chr3:83179335-83205759 (+)
JF1/MsJ ENSUMUG00000024160
protein coding gene Chr3:83910215-83936736 (+)
LP/J ENSMUSG00230035411
protein coding gene Chr3:86354595-86367399 (+)
NOD/ShiLtJ ENSMUSG00190045617
protein coding gene Chr3:84631635-84658059 (+)
NZO/HlLtJ ENSMUSG00225006696
protein coding gene Chr3:89108900-89121703 (+)
PWK/PhJ ENSLUMG00010051628
protein coding gene Chr3:84002881-84029366 (+)
SPRET/EiJ ENSMSPG00010046917
protein coding gene Chr3:84832542-84857358 (+)
WSB/EiJ ENSIUOG00005047895
protein coding gene Chr3:84602700-84629256 (+)



Homology
more
  • Human Ortholog
    FCRL1, Fc receptor like 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FCRL1, Fc receptor like 1
  • Synonyms
    CD307a, FCRH1, IFGP1, IRTA5
  • Links
    NCBI Gene ID: 115350
    UniProt: Q96LA6

  • Chr Location
    1q23.1; chr1:157792249-157820183 (-)  GRCh38

  • Human Ortholog
    FCRL2, Fc receptor like 2
  • Synonyms
    CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C
  • Links
    NCBI Gene ID: 79368
    UniProt: Q96LA5

  • Chr Location
    1q23.1; chr1:157745733-157777269 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Fcrl1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059994 Ensembl Gene Model | MGI Sequence Detail 26548 C57BL/6J ±  kb
transcript ENSMUST00000163661 Ensembl | MGI Sequence Detail 1649 Not Applicable  
polypeptide ENSMUSP00000130936 Ensembl | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 5
References
more
  • Summaries
    All 35
    Diseases 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:317170 DeLuca JM, et al., FCRL1 Regulates B Cell Receptor-Induced ERK Activation through GRB2. J Immunol. 2021 Dec 1;207(11):2688-2698

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory