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Mfsd4a Gene Detail
Summary
  • Symbol
    Mfsd4a
  • Name
    major facilitator superfamily domain containing 4A
  • Synonyms
    A930031D07Rik, Mfsd4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442786
    NCBI Gene: 213006
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:131950544-131995800 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 57.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3104 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442786
 protein coding gene Chr1:131947543-131997400 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016465
 protein coding gene Chr1:135485239-135531747 (-)
A/J MGP_AJ_G0016448
 protein coding gene Chr1:130464800-130510008 (-)
AKR/J MGP_AKRJ_G0016413
 protein coding gene Chr1:134296791-134342085 (-)
BALB/cJ MGP_BALBcJ_G0016408
 protein coding gene Chr1:130785488-130833056 (-)
C3H/HeJ MGP_C3HHeJ_G0016234
 protein coding gene Chr1:134444857-134492965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016869
 protein coding gene Chr1:140522469-140569104 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014580
 protein coding gene Chr1:123608587-123654077 (-)
CAST/EiJ MGP_CASTEiJ_G0015814
 protein coding gene Chr1:133443771-133492670 (-)
CBA/J MGP_CBAJ_G0016206
 protein coding gene Chr1:145304000-145352180 (-)
DBA/2J MGP_DBA2J_G0016313
 protein coding gene Chr1:129429378-129474904 (-)
FVB/NJ MGP_FVBNJ_G0016312
 protein coding gene Chr1:128052212-128097899 (-)
LP/J MGP_LPJ_G0016384
 protein coding gene Chr1:136792254-136838163 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016337
 protein coding gene Chr1:151097048-151148777 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016905
 protein coding gene Chr1:134058592-134104206 (-)
PWK/PhJ MGP_PWKPhJ_G0015600
 protein coding gene Chr1:128403985-128451560 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015387
 protein coding gene Chr1:133000520-133047098 (-)
WSB/EiJ MGP_WSBEiJ_G0015876
 protein coding gene Chr1:134043855-134090449 (-)



Homology
more
  • Human Ortholog
    MFSD4A, major facilitator superfamily domain containing 4A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MFSD4A, major facilitator superfamily domain containing 4A
  • Synonyms
    MFSD4, SLC60A1, UNQ3064
  • Links
    NCBI Gene ID: 148808
    UniProt: Q8N468

  • Chr Location
    1q32.1; chr1:205568885-205602918 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    39
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059149 Ensembl Gene Model | MGI Sequence Detail 45257 C57BL/6J ±  kb
transcript ENSMUST00000144548 Ensembl | MGI Sequence Detail 3288 Not Applicable  
polypeptide ENSMUSP00000116282 Ensembl | MGI Sequence Detail 512 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000031750 major facilitator superfamily domain-containing protein 4A
    (term hierarchy)
  • InterPro Domains
    IPR011701 Major facilitator superfamily
    IPR036259 MFS transporter superfamily
  • GlyGen
    Q6PDC8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 39
    cDNA 39

    Microarray probesets 7
Other
Accession IDs
less
MGI:2138352
References
more
  • Summaries
    All 34
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory