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Mroh1 Gene Detail
Summary
  • Symbol
    Mroh1
  • Name
    maestro heat-like repeat family member 1
  • Synonyms
    D330001F17Rik, Heatr7a, mKIAA1833
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442558
    NCBI Gene: 223658
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76264638-76337239 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 35.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2069 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442558
 protein coding gene Chr15:76264461-76337239 (+)
129S1/SvImJ ENSMUSG00200050492
 protein coding gene Chr15:73390789-73451440 (+)
A/J ENSMUSG00195050338
 protein coding gene Chr15:73365248-73425913 (+)
AKR/J ENSMUSG00220047981
 protein coding gene Chr15:73376255-73436914 (+)
BALB/cJ ENSMUSG00180051491
 protein coding gene Chr15:73190390-73251052 (+)
C3H/HeJ ENSMUSG00175051847
 protein coding gene Chr15:73553814-73614479 (+)
C57BL/6NJ ENSMUSG00215048353
 protein coding gene Chr15:73282614-73343276 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019927
 protein coding gene Chr15:70328676-70403630 (+)
CAST/EiJ ENSTCUG00005044205
 protein coding gene Chr15:72896262-72956905 (+)
CBA/J ENSMUSG00210037163
 protein coding gene Chr15:73329051-73389688 (+)
DBA/2J ENSMUSG00185048906
 protein coding gene Chr15:73306220-73366877 (+)
FVB/NJ ENSMUSG00205043538
 protein coding gene Chr15:73058506-73119172 (+)
JF1/MsJ ENSUMUG00000049643
 protein coding gene Chr15:72957158-73019371 (+)
LP/J ENSMUSG00230052548
 protein coding gene Chr15:76671749-76732416 (+)
NOD/ShiLtJ ENSMUSG00190051920
 protein coding gene Chr15:73311386-73372954 (+)
NZO/HlLtJ ENSMUSG00225050214
 protein coding gene Chr15:76976552-77038118 (+)
PWK/PhJ ENSLUMG00010049271
 protein coding gene Chr15:73249072-73311071 (+)
SPRET/EiJ ENSMSPG00010043853
 protein coding gene Chr15:74842700-74917027 (+)
WSB/EiJ ENSIUOG00005036946
 protein coding gene Chr15:73369016-73439113 (+)



Homology
more
  • Human Ortholog
    MROH1, maestro heat like repeat family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH1, maestro heat like repeat family member 1
  • Synonyms
    HEATR7A, HPO27
  • Links
    NCBI Gene ID: 727957
    UniProt: Q8NDA8

  • Chr Location
    8q24.3; chr8:144147997-144262470 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    3
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Mroh1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    63 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    103
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223658 NCBI Gene Model | MGI Sequence Detail 72602 C57BL/6J ±  kb
transcript NM_175457 RefSeq | MGI Sequence Detail 5269 C57BL/6  
polypeptide E0CZ22 UniProt | EBI | MGI Sequence Detail 1640 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 103
    cDNA 103

    Microarray probesets 6
References
more
  • Summaries
    All 55
    Diseases 1
    Gene Ontology 6
    Phenotypes 29
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory