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Ppp1r9a Gene Detail
Summary
  • Symbol
    Ppp1r9a
  • Name
    protein phosphatase 1, regulatory subunit 9A
  • Synonyms
    2810430P21Rik, 4930518N04Rik, A230094E16Rik, mKIAA1222, neurabin-I, Neurabin I, NRB
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442401
    NCBI Gene: 243725
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:4902917-5165661 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 1.86 cM, cytoband A1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6930 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442401
 protein coding gene Chr6:4902702-5165661 (+)
129S1/SvImJ ENSMUSG00200001383
 protein coding gene Chr6:1979038-2242089 (+)
A/J ENSMUSG00195001857
 protein coding gene Chr6:1860311-2123378 (+)
AKR/J ENSMUSG00220020636
 protein coding gene Chr6:1767560-2030686 (+)
BALB/cJ ENSMUSG00180001456
 protein coding gene Chr6:1995867-2258915 (+)
C3H/HeJ ENSMUSG00175007147
 protein coding gene Chr6:1824394-2087431 (+)
C57BL/6NJ ENSMUSG00215008883
 protein coding gene Chr6:1955544-2218536 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028079
 protein coding gene Chr6:1383953-1643312 (+)
CAST/EiJ ENSTCUG00005025227
 protein coding gene Chr6:1842353-2106266 (+)
CBA/J ENSMUSG00210021160
 protein coding gene Chr6:1761414-2024481 (+)
DBA/2J ENSMUSG00185025122
 protein coding gene Chr6:1956244-2219285 (+)
FVB/NJ ENSMUSG00205013119
 protein coding gene Chr6:1951608-2238801 (+)
JF1/MsJ ENSUMUG00000008973
 protein coding gene Chr6:1961205-2226657 (+)
LP/J ENSMUSG00230016386
 protein coding gene Chr6:2955937-3218991 (+)
NOD/ShiLtJ ENSMUSG00190016171
 protein coding gene Chr6:1681462-1944502 (+)
NZO/HlLtJ ENSMUSG00225018382
 protein coding gene Chr6:4785286-5053786 (+)
PWK/PhJ ENSLUMG00010023730
 protein coding gene Chr6:1749930-2015685 (+)
SPRET/EiJ ENSMSPG00010002343
 protein coding gene Chr6:1645308-1906985 (+)
WSB/EiJ ENSIUOG00005004066
 protein coding gene Chr6:1941469-2205384 (+)



Homology
more
  • Human Ortholog
    PPP1R9A, protein phosphatase 1 regulatory subunit 9A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R9A, protein phosphatase 1 regulatory subunit 9A
  • Synonyms
    Neurabin-I, NRB1, NRBI
  • Links
    NCBI Gene ID: 55607
    UniProt: Q9ULJ8

  • Chr Location
    7q21.3; chr7:94907202-95296415 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit defects in dopamine-mediated neuromodulation, deficient long-term potentiation at corticostriatal synapses, increased spontaneous excitatory post-synaptic current frequency, and enhanced locomotor activationin response to cocaine treatment.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    53
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    700
  • Tissues
    41
  • cDNA Data
    55
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032827 Ensembl Gene Model | MGI Sequence Detail 262745 C57BL/6J ±  kb
transcript ENSMUST00000177456 Ensembl | MGI Sequence Detail 3975 Not Applicable  
polypeptide ENSMUSP00000134943 Ensembl | MGI Sequence Detail 1292 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 56
    Primer pair 4
    Other 1
    Antibodies 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919984, MGI:2141739
References
more
  • Summaries
    All 57
    Developmental Gene Expression 9
    Gene Ontology 7
    Phenotypes 16
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:389864 Murata K, et al., A novel miniTurbo knock-in mouse reveals a protein interaction network of USP46 in the brain. Exp Anim. 2026 Jan 1;75(1):63-72
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory