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Sybu Gene Detail
Summary
  • Symbol
    Sybu
  • Name
    syntabulin (syntaxin-interacting)
  • Synonyms
    5730410E15Rik, A830027B17Rik, Golsyn/Syntabulin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442392
    NCBI Gene: 319613
  • Alliance
    genome feature page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:44535252-44651459 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 16.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2961 from dbSNP Build 142
  • Strain Annotations
    24
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442392
 protein coding gene Chr15:44535252-44651466 (-)
129S1/SvImJ ENSMUSGG00200054843
 protein coding gene Chr15:41460560-41537306 (-)
A/J ENSMUSGG00195055291
 protein coding gene Chr15:41472396-41549156 (-)
A/J ENSMUSG00195005438
 protein coding gene Chr15:41561447-41588535 (-)
AKR/J ENSMUSG00220017913
 protein coding gene Chr15:41525213-41552308 (-)
AKR/J ENSMUSGG00220054835
 protein coding gene Chr15:41436012-41512922 (-)
BALB/cJ ENSMUSGG00180055435
 protein coding gene Chr15:41455753-41532717 (-)
BALB/cJ ENSMUSG00180004472
 protein coding gene Chr15:41545013-41572102 (-)
C3H/HeJ ENSMUSG00175020001
 protein coding gene Chr15:41783620-41810714 (-)
C3H/HeJ ENSMUSGG00175054741
 protein coding gene Chr15:41694419-41771326 (-)
C57BL/6NJ ENSMUSG00215003225
 protein coding gene Chr15:41558952-41586041 (-)
C57BL/6NJ ENSMUSGG00215055617
 protein coding gene Chr15:41469683-41546650 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019776
 protein coding gene Chr15:39165071-39275476 (-)
CAST/EiJ ENSTCUGG00005053895
 protein coding gene Chr15:41438115-41514842 (-)
CBA/J ENSMUSGG00210054880
 protein coding gene Chr15:41574035-41650782 (-)
DBA/2J ENSMUSGG00185057619
 protein coding gene Chr15:41539580-41616324 (-)
FVB/NJ ENSMUSGG00205054499
 protein coding gene Chr15:41486889-41563640 (-)
JF1/MsJ ENSUMUGG00000058191
 protein coding gene Chr15:41412786-41483392 (-)
LP/J ENSMUSGG00230055717
 protein coding gene Chr15:44844205-44920959 (-)
NOD/ShiLtJ ENSMUSGG00190054965
 protein coding gene Chr15:41510839-41587581 (-)
NZO/HlLtJ ENSMUSGG00225055543
 protein coding gene Chr15:45213791-45285673 (-)
PWK/PhJ ENSLUMGG00010054199
 protein coding gene Chr15:41596070-41666783 (-)
SPRET/EiJ ENSMSPGG00010052302
 protein coding gene Chr15:42470505-42548710 (-)
WSB/EiJ ENSIUOGG00005054073
 protein coding gene Chr15:41528141-41604856 (-)



Homology
more
  • Human Ortholog
    SYBU, syntabulin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYBU, syntabulin
  • Synonyms
    GOLSYN, OCSYN, SNPHL
  • Links
    NCBI Gene ID: 55638
    UniProt: Q9NX95

  • Chr Location
    8q23.2; chr8:109573978-109691791 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    863
  • Tissues
    50
  • cDNA Data
    15
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022340 Ensembl Gene Model | MGI Sequence Detail 116208 C57BL/6J ±  kb
    transcript ENSMUST00000090057 Ensembl | MGI Sequence Detail 3230 Not Applicable  
    polypeptide ENSMUSP00000087511 Ensembl | MGI Sequence Detail 793 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 15
      Other 4
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2442683
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 6
      Gene Ontology 7
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory