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Amz1 Gene Detail
Summary
  • Symbol
    Amz1
  • Name
    archaelysin family metallopeptidase 1
  • Synonyms
    6530401C20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442258
    NCBI Gene: 231842
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:140709882-140739067 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 79.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    890 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442258
 protein coding gene Chr5:140709882-140747194 (+)
129S1/SvImJ ENSMUSG00200040911
 protein coding gene Chr5:134577223-134614690 (+)
A/J ENSMUSG00195045020
 protein coding gene Chr5:134201502-134238994 (+)
AKR/J ENSMUSG00220022443
 protein coding gene Chr5:133458591-133495685 (+)
BALB/cJ ENSMUSG00180030878
 protein coding gene Chr5:134302032-134339517 (+)
C3H/HeJ ENSMUSG00175044067
 protein coding gene Chr5:136222869-136260387 (+)
C57BL/6NJ ENSMUSG00215036886
 protein coding gene Chr5:134155791-134193269 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027955
 protein coding gene Chr5:133441252-133478176 (+)
CAST/EiJ ENSTCUG00005029567
 protein coding gene Chr5:133611771-133649284 (+)
CBA/J ENSMUSG00210022668
 protein coding gene Chr5:135039779-135077305 (+)
DBA/2J ENSMUSG00185053377
 protein coding gene Chr5:138054986-138092456 (+)
FVB/NJ ENSMUSG00205022560
 protein coding gene Chr5:133860065-133897550 (+)
JF1/MsJ ENSUMUG00000043794
 protein coding gene Chr5:140935482-140973759 (+)
LP/J ENSMUSG00230027429
 protein coding gene Chr5:142170710-142208193 (+)
NOD/ShiLtJ ENSMUSG00190037152
 protein coding gene Chr5:133997309-134034789 (+)
NZO/HlLtJ ENSMUSG00225023366
 protein coding gene Chr5:149645656-149682990 (+)
PWK/PhJ ENSLUMG00010018396
 protein coding gene Chr5:132657562-132695733 (+)
SPRET/EiJ ENSMSPG00010035726
 protein coding gene Chr5:136276347-136289832 (+)
WSB/EiJ ENSIUOG00005036472
 protein coding gene Chr5:136530880-136568585 (+)



Homology
more
  • Human Ortholog
    AMZ1, archaelysin family metallopeptidase 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AMZ1, archaelysin family metallopeptidase 1
  • Links
    NCBI Gene ID: 155185
    UniProt: Q400G9

  • Chr Location
    7p22.3; chr7:2679276-2775500 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231842 NCBI Gene Model | MGI Sequence Detail 29186 C57BL/6J ±  kb
transcript NM_173405 RefSeq | MGI Sequence Detail 2685 C57BL/6  
polypeptide Q8BVF9 UniProt | EBI | MGI Sequence Detail 502 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory