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Zfp446 Gene Detail
Summary
  • Symbol
    Zfp446
  • Name
    zinc finger protein 446
  • Synonyms
    A630035I11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442185
    NCBI Gene: 269870
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:12711726-12718323 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 7.71 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    440 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442185
 protein coding gene Chr7:12711726-12719641 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031659
 protein coding gene Chr7:10375969-10382472 (+)
A/J MGP_AJ_G0031632
 protein coding gene Chr7:10222509-10229012 (+)
AKR/J MGP_AKRJ_G0031555
 protein coding gene Chr7:10453278-10459782 (+)
BALB/cJ MGP_BALBcJ_G0031637
 protein coding gene Chr7:10337683-10344186 (+)
C3H/HeJ MGP_C3HHeJ_G0031359
 protein coding gene Chr7:10552382-10558885 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032101
 protein coding gene Chr7:10913042-10919534 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029195
 protein coding gene Chr7:11816312-11824548 (+)
CAST/EiJ MGP_CASTEiJ_G0030717
 protein coding gene Chr7:8110520-8117011 (+)
CBA/J MGP_CBAJ_G0031316
 protein coding gene Chr7:11124677-11131180 (+)
DBA/2J MGP_DBA2J_G0031474
 protein coding gene Chr7:10102906-10109409 (+)
FVB/NJ MGP_FVBNJ_G0031430
 protein coding gene Chr7:10106415-10112908 (+)
LP/J MGP_LPJ_G0031561
 protein coding gene Chr7:10468667-10475170 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031465
 protein coding gene Chr7:11216622-11223115 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032131
 protein coding gene Chr7:10235009-10241501 (+)
PWK/PhJ MGP_PWKPhJ_G0030445
 protein coding gene Chr7:8591018-8597506 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030271
 protein coding gene Chr7:6346765-6353237 (+)
WSB/EiJ MGP_WSBEiJ_G0030813
 protein coding gene Chr7:10267628-10274126 (+)



Homology
more
  • Human Ortholog
    ZNF446, zinc finger protein 446
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF446, zinc finger protein 446
  • Synonyms
    ZKSCAN20, ZSCAN30, ZSCAN52
  • Links
    NCBI Gene ID: 55663
    UniProt: Q9NWS9

  • Chr Location
    19q13.43; chr19:58474017-58489533 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    25
  • cDNA Data
    24
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 269870 NCBI Gene Model | MGI Sequence Detail 6598 C57BL/6J ±  kb
transcript NM_001168562 RefSeq | MGI Sequence Detail 3581 C57BL/6  
polypeptide NP_780767 RefSeq | MGI Sequence Detail 523 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 25
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:3034582, MGI:3034586
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory