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Cdcp1 Gene Detail
Summary
  • Symbol
    Cdcp1
  • Name
    CUB domain containing protein 1
  • Synonyms
    9030022E12Rik, E030027H19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442010
    NCBI Gene: 109332
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:122999889-123045103 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 73.92 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    202 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442010
 protein coding gene Chr9:122999870-123045175 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035474
 protein coding gene Chr9:126196800-126234958 (-)
A/J MGP_AJ_G0035455
 protein coding gene Chr9:121369166-121408711 (-)
AKR/J MGP_AKRJ_G0035388
 protein coding gene Chr9:124634821-124674355 (-)
BALB/cJ MGP_BALBcJ_G0035451
 protein coding gene Chr9:121295776-121338762 (-)
C3H/HeJ MGP_C3HHeJ_G0035158
 protein coding gene Chr9:125075045-125116135 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035974
 protein coding gene Chr9:129689194-129735346 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032856
 protein coding gene Chr9:118510000-118547757 (-)
CAST/EiJ MGP_CASTEiJ_G0034463
 protein coding gene Chr9:125103139-125145731 (-)
CBA/J MGP_CBAJ_G0035126
 protein coding gene Chr9:134398191-134438625 (-)
DBA/2J MGP_DBA2J_G0035285
 protein coding gene Chr9:120819947-120866185 (-)
FVB/NJ MGP_FVBNJ_G0035232
 protein coding gene Chr9:119725938-119770832 (-)
LP/J MGP_LPJ_G0035364
 protein coding gene Chr9:126531615-126574704 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035273
 protein coding gene Chr9:135244013-135290749 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035993
 protein coding gene Chr9:125091414-125131990 (-)
PWK/PhJ MGP_PWKPhJ_G0034167
 protein coding gene Chr9:121273834-121313798 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034004
 protein coding gene Chr9:125196997-125234411 (-)
WSB/EiJ MGP_WSBEiJ_G0034583
 protein coding gene Chr9:124937334-124975445 (-)



Homology
more
  • Human Ortholog
    CDCP1, CUB domain containing protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDCP1, CUB domain containing protein 1
  • Synonyms
    CD318, SIMA135, TRASK
  • Links
    NCBI Gene ID: 64866
    neXtProt AC: NX_Q9H5V8
    UniProt: Q9H5V8

  • Chr Location
    3p21.31; chr3:45082277-45146482 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 3 genetic backgrounds
    10 phenotypes from multigenic genotypes
    16 phenotype references
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    857
  • Tissues
    26
  • cDNA Data
    54
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035498 Ensembl Gene Model | MGI Sequence Detail 45215 C57BL/6J ±  kb
transcript ENSMUST00000039229 Ensembl | MGI Sequence Detail 5310 Not Applicable  
polypeptide ENSMUSP00000042057 Ensembl | MGI Sequence Detail 833 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925928, MGI:2142933
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 16
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:332189 Zhang L, et al., CDCP1 regulates retinal pigmented epithelial barrier integrity for the development of experimental autoimmune uveitis. JCI Insight. 2022 Sep 22;7(18)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory