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Mycbpap Gene Detail
Summary
  • Symbol
    Mycbpap
  • Name
    MYCBP associated protein
  • Synonyms
    4932408B01Rik, AMAP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388726
    NCBI Gene: 104601
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:94392173-94412568 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 58.90 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388726
 protein coding gene Chr11:94392173-94423219 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018959
 protein coding gene Chr11:96597020-96620485 (-)
A/J MGP_AJ_G0018927
 protein coding gene Chr11:92734129-92754160 (-)
AKR/J MGP_AKRJ_G0018897
 protein coding gene Chr11:95619024-95639298 (-)
BALB/cJ MGP_BALBcJ_G0018900
 protein coding gene Chr11:93184498-93204795 (-)
C3H/HeJ MGP_C3HHeJ_G0018714
 protein coding gene Chr11:95702994-95723503 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019352
 protein coding gene Chr11:99604414-99627196 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016983
 protein coding gene Chr11:90228635-90249707 (-)
CAST/EiJ MGP_CASTEiJ_G0018269
 protein coding gene Chr11:96420255-96440970 (-)
CBA/J MGP_CBAJ_G0018685
 protein coding gene Chr11:103743332-103765647 (-)
DBA/2J MGP_DBA2J_G0018793
 protein coding gene Chr11:92310405-92330644 (-)
FVB/NJ MGP_FVBNJ_G0018782
 protein coding gene Chr11:91731320-91751549 (-)
LP/J MGP_LPJ_G0018863
 protein coding gene Chr11:97143088-97164591 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018809
 protein coding gene Chr11:103764226-103785779 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019392
 protein coding gene Chr11:95846358-95867917 (-)
PWK/PhJ MGP_PWKPhJ_G0018039
 protein coding gene Chr11:93243532-93265223 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017829
 protein coding gene Chr11:95507529-95529457 (-)
WSB/EiJ MGP_WSBEiJ_G0018318
 protein coding gene Chr11:95726900-95750039 (-)



Homology
more
  • Human Ortholog
    MYCBPAP, MYCBP associated protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYCBPAP, MYCBP associated protein
  • Synonyms
    AMAP-1, AMAP1
  • Links
    NCBI Gene ID: 84073
    UniProt: Q8TBZ2

  • Chr Location
    17q21.33; chr17:50507778-50531501 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a null allele are infertile with oligoasthenoteratozoospermia and impaired centrosome-nuclear envolope docking and sperm tail biogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    4
  • cDNA Data
    18
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039110 Ensembl Gene Model | MGI Sequence Detail 20396 C57BL/6J ±  kb
    transcript ENSMUST00000239238 Ensembl | MGI Sequence Detail 3207 Not Applicable  
    polypeptide ENSMUSP00000159222 Ensembl | MGI Sequence Detail 942 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2144505
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:367324 Wang H, et al., MYCBPAP is a central apparatus protein required for centrosome-nuclear envelope docking and sperm tail biogenesis in mice. J Cell Sci. 2024 Aug 15;137(16):jcs261962
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory