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Taf3 Gene Detail
Summary
  • Symbol
    Taf3
  • Name
    TATA-box binding protein associated factor 3
  • Synonyms
    4933439M23Rik, mTAFII140
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388097
    NCBI Gene: 209361
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:9919363-10053407 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 6.74 cM, cytoband A1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    541 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388097
protein coding gene Chr2:9919363-10053420 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025336
protein coding gene Chr2:7252192-7400736 (-)
A/J MGP_AJ_G0025313
protein coding gene Chr2:6929966-7066908 (-)
AKR/J MGP_AKRJ_G0025282
protein coding gene Chr2:7145743-7287534 (-)
BALB/cJ MGP_BALBcJ_G0025309
protein coding gene Chr2:6930762-7068947 (-)
C3H/HeJ MGP_C3HHeJ_G0025069
protein coding gene Chr2:7104213-7244735 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025751
protein coding gene Chr2:7448281-7589382 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023165
protein coding gene Chr2:6439218-6580746 (-)
CAST/EiJ MGP_CASTEiJ_G0024532
protein coding gene Chr2:7121666-7274018 (-)
CBA/J MGP_CBAJ_G0025048
protein coding gene Chr2:7744444-7896708 (-)
DBA/2J MGP_DBA2J_G0025180
protein coding gene Chr2:6861246-6999454 (-)
FVB/NJ MGP_FVBNJ_G0025142
protein coding gene Chr2:6801403-6940298 (-)
LP/J MGP_LPJ_G0025266
protein coding gene Chr2:7127808-7273963 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025174
protein coding gene Chr2:7736561-7879365 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025809
protein coding gene Chr2:7101077-7244938 (-)
PWK/PhJ MGP_PWKPhJ_G0024283
protein coding gene Chr2:6843309-6980675 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024083
protein coding gene Chr2:7086053-7234435 (-)
WSB/EiJ MGP_WSBEiJ_G0024602
protein coding gene Chr2:7197230-7337187 (-)



Homology
more
  • Human Ortholog
    TAF3, TATA-box binding protein associated factor 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAF3, TATA-box binding protein associated factor 3
  • Synonyms
    TAF140, TAFII140, TAFII-140
  • Links
    NCBI Gene ID: 83860
    neXtProt AC: NX_Q5VWG9
    UniProt: Q5VWG9

  • Chr Location
    10p14; chr10:7818497-8016631 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025782 Ensembl Gene Model | MGI Sequence Detail 134045 C57BL/6J ±  kb
transcript ENSMUST00000026888 Ensembl | MGI Sequence Detail 4792 Not Applicable  
polypeptide ENSMUSP00000026888 Ensembl | MGI Sequence Detail 932 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 24
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1918534, MGI:2139366
References
more
  • Summaries
    All 52
    Developmental Gene Expression 10
    Gene Ontology 10
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:337771 El-Saafin F, et al., Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory