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Fam120c Gene Detail
Summary
  • Symbol
    Fam120c
  • Name
    family with sequence similarity 120, member C
  • Synonyms
    D930001I21Rik, orf34
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387687
    NCBI Gene: 207375
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:150127171-150254838 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 68.46 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2362 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387687
 protein coding gene ChrX:150125515-150257135 (+)
129S1/SvImJ ENSMUSG00200029825
 protein coding gene ChrX:126932867-127060539 (+)
A/J ENSMUSG00195019567
 protein coding gene ChrX:131934459-132073467 (+)
AKR/J ENSMUSG00220029403
 protein coding gene ChrX:123932220-124059892 (+)
BALB/cJ ENSMUSG00180036998
 protein coding gene ChrX:127317488-127449264 (+)
C3H/HeJ ENSMUSG00175026285
 protein coding gene ChrX:131841503-131969178 (+)
C57BL/6NJ ENSMUSG00215016322
 protein coding gene ChrX:127606587-127734257 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033493
 protein coding gene ChrX:140025359-140144016 (+)
CAST/EiJ ENSTCUG00005033848
 protein coding gene ChrX:129632081-129762600 (+)
CBA/J ENSMUSG00210029035
 protein coding gene ChrX:129318855-129446528 (+)
DBA/2J ENSMUSG00185043889
 protein coding gene ChrX:144140317-144267985 (+)
FVB/NJ ENSMUSG00205024079
 protein coding gene ChrX:127888790-128020590 (+)
JF1/MsJ ENSUMUG00000026576
 protein coding gene ChrX:164341401-164468205 (+)
LP/J ENSMUSG00230032355
 protein coding gene ChrX:150942466-151070133 (+)
NOD/ShiLtJ ENSMUSG00190034125
 protein coding gene ChrX:128435980-128567769 (+)
NZO/HlLtJ ENSMUSG00225042038
 protein coding gene ChrX:154439262-154566924 (+)
PWK/PhJ ENSLUMG00010032768
 protein coding gene ChrX:125872613-125999477 (+)
SPRET/EiJ ENSMSPG00010039142
 protein coding gene ChrX:130716951-130843698 (+)
WSB/EiJ ENSIUOG00005039076
 protein coding gene ChrX:128906931-129038788 (+)



Homology
more
  • Human Ortholog
    FAM120C, family with sequence similarity 120 member C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM120C, family with sequence similarity 120 member C
  • Synonyms
    CXorf17, ORF34
  • Links
    NCBI Gene ID: 54954
    UniProt: Q9NX05

  • Chr Location
    Xp11.22; chrX:54068324-54183281 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 2 alleles in 2 genetic backgrounds
    9 images
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male chimeras hemizygous for a gene trapped allele appear phenotypically normal at E9.5.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    610
  • Tissues
    12
  • cDNA Data
    9
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025262 Ensembl Gene Model | MGI Sequence Detail 127668 C57BL/6J ±  kb
    transcript ENSMUST00000073364 Ensembl | MGI Sequence Detail 5463 Not Applicable  
    polypeptide ENSMUSP00000073082 Ensembl | MGI Sequence Detail 1091 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2443307
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory