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Csrnp2 Gene Detail
Summary
  • Symbol
    Csrnp2
  • Name
    cysteine-serine-rich nuclear protein 2
  • Synonyms
    CSRNP-2, MGC:28165
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386852
    NCBI Gene: 207785
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:100377451-100393120 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    348 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386852
 protein coding gene Chr15:100377451-100393369 (-)
129S1/SvImJ ENSMUSG00200050907
 protein coding gene Chr15:97583031-97598967 (-)
A/J ENSMUSG00195038650
 protein coding gene Chr15:97460817-97476735 (-)
AKR/J ENSMUSG00220043811
 protein coding gene Chr15:97454050-97469970 (-)
BALB/cJ ENSMUSG00180036214
 protein coding gene Chr15:97358857-97374773 (-)
C3H/HeJ ENSMUSG00175040716
 protein coding gene Chr15:97640799-97656718 (-)
C57BL/6NJ ENSMUSG00215050193
 protein coding gene Chr15:97415895-97431814 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020292
 protein coding gene Chr15:94177414-94192922 (-)
CAST/EiJ ENSTCUG00005042825
 protein coding gene Chr15:96897403-96913473 (-)
CBA/J ENSMUSG00210028754
 protein coding gene Chr15:97415702-97431616 (-)
DBA/2J ENSMUSG00185038162
 protein coding gene Chr15:97460453-97476372 (-)
FVB/NJ ENSMUSG00205026043
 protein coding gene Chr15:97164906-97180824 (-)
JF1/MsJ ENSUMUG00000052609
 protein coding gene Chr15:96925287-96941291 (-)
LP/J ENSMUSG00230039482
 protein coding gene Chr15:100806365-100822301 (-)
NOD/ShiLtJ ENSMUSG00190047056
 protein coding gene Chr15:97391645-97407579 (-)
NZO/HlLtJ ENSMUSG00225041601
 protein coding gene Chr15:101009777-101025711 (-)
PWK/PhJ ENSLUMG00010038650
 protein coding gene Chr15:97128021-97143956 (-)
SPRET/EiJ ENSMSPG00010048398
 protein coding gene Chr15:98949275-98965198 (-)
WSB/EiJ ENSIUOG00005035901
 protein coding gene Chr15:97546800-97562735 (-)



Homology
more
  • Human Ortholog
    CSRNP2, cysteine and serine rich nuclear protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSRNP2, cysteine and serine rich nuclear protein 2
  • Synonyms
    C12ORF2, C12orf22, FAM130A1, PPP1R72, TAIP-12
  • Links
    NCBI Gene ID: 81566
    UniProt: Q9H175

  • Chr Location
    12q13.12; chr12:51061205-51083664 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from multigenic genotypes
    28 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    6
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Csrnp2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    19 strains or lines available
Mice homozygous for a knock-out allele are viable, fertile and healthy and display normal development, hematopoiesis and T cell function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    612
  • Tissues
    13
  • cDNA Data
    49
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 207785 NCBI Gene Model | MGI Sequence Detail 15670 C57BL/6J ±  kb
transcript NM_153407 RefSeq | MGI Sequence Detail 4126 C57BL/6  
polypeptide Q8BGQ2 UniProt | EBI | MGI Sequence Detail 534 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005956 cysteine/serine-rich nuclear protein 2
    (term hierarchy)
  • InterPro Domains
    IPR023260 Cysteine/serine-rich nuclear protein family
    IPR031972 Cysteine/serine-rich nuclear protein, N-terminal domain
Molecular
Reagents
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  • All nucleic 50
    cDNA 50
    Antibodies 1

    Microarray probesets 2
References
more
  • Summaries
    All 54
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 7
    Phenotypes 28
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory