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Nomo1 Gene Detail
Summary
  • Symbol
    Nomo1
  • Name
    nodal modulator 1
  • Synonyms
    D7Ertd156e, MGC:37454, MGC:37848, Nomo, PM5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385850
    NCBI Gene: 211548
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45683122-45733636 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    836 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385850
 protein coding gene Chr7:45683120-45733636 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032258
 protein coding gene Chr7:46373526-46429153 (+)
A/J MGP_AJ_G0032237
 protein coding gene Chr7:45435390-45487168 (+)
AKR/J MGP_AKRJ_G0032173
 protein coding gene Chr7:46721030-46774457 (+)
BALB/cJ MGP_BALBcJ_G0032249
 protein coding gene Chr7:45437064-45487492 (+)
C3H/HeJ MGP_C3HHeJ_G0031964
 protein coding gene Chr7:47212990-47267841 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032741
 protein coding gene Chr7:48653233-48706893 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029755
 protein coding gene Chr7:47982310-48033756 (+)
CAST/EiJ MGP_CASTEiJ_G0031292
 protein coding gene Chr7:38645757-38708521 (+)
CBA/J MGP_CBAJ_G0031929
 protein coding gene Chr7:50278200-50333812 (+)
DBA/2J MGP_DBA2J_G0032086
 protein coding gene Chr7:45116518-45171766 (+)
FVB/NJ MGP_FVBNJ_G0032038
 protein coding gene Chr7:44901396-44956715 (+)
LP/J MGP_LPJ_G0032165
 protein coding gene Chr7:47084480-47135726 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032075
 protein coding gene Chr7:48926340-48985150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032756
 protein coding gene Chr7:45925561-45980547 (+)
PWK/PhJ MGP_PWKPhJ_G0031015
 protein coding gene Chr7:38488769-38542443 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030853
 protein coding gene Chr7:33942851-34015057 (+)
WSB/EiJ MGP_WSBEiJ_G0031410
 protein coding gene Chr7:46422086-46475232 (+)



Homology
more
  • Human Ortholog
    NOMO1, NODAL modulator 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NOMO1, NODAL modulator 1
  • Synonyms
    Nomo, PM5
  • Links
    NCBI Gene ID: 23420
    neXtProt AC: NX_Q15155
    UniProt: P69849, Q15155

  • Chr Location
    16p13.11; chr16:14833721-14896157 (+)  GRCh38
  • Human Ortholog
    NOMO2, NODAL modulator 2
  • Synonyms
    Nomo, PM5
  • Links
    NCBI Gene ID: 283820
    neXtProt AC: NX_Q5JPE7
    UniProt: Q5JPE7

  • Chr Location
    16p12.3; chr16:18417325-18562211 (-)  GRCh38
  • Human Ortholog
    NOMO3, NODAL modulator 3
  • Synonyms
    Nomo
  • Links
    NCBI Gene ID: 408050
    neXtProt AC: NX_P69849
    UniProt: P69849

  • Chr Location
    16p13.11; chr16:16232506-16300806 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    781
  • Tissues
    36
  • cDNA Data
    149
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030835 Ensembl Gene Model | MGI Sequence Detail 50515 C57BL/6J ±  kb
transcript ENSMUST00000033121 Ensembl | MGI Sequence Detail 4257 Not Applicable  
polypeptide ENSMUSP00000033121 Ensembl | MGI Sequence Detail 1214 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 152
    cDNA 150
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1098832
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:327863 Perez-Garcia J, et al., Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration. Cancers (Basel). 2022 Aug 20;14(16)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory