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Gtpbp10 Gene Detail
Summary
  • Symbol
    Gtpbp10
  • Name
    GTP-binding protein 10 (putative)
  • Synonyms
    4930545J22Rik, MGC:30495
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385599
    NCBI Gene: 207704
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:5587454-5609538 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 3.02 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    802 from dbSNP Build 142
  • Strain Annotations
    22
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385599
 protein coding gene Chr5:5587454-5609541 (-)
129S1/SvImJ ENSMUSG00200002538
 protein coding gene Chr5:2250879-2272963 (-)
A/J ENSMUSG00195007046
 protein coding gene Chr5:2280484-2302569 (-)
AKR/J ENSMUSG00220001826
 protein coding gene Chr5:2184752-2206836 (-)
BALB/cJ ENSMUSG00180016679
 protein coding gene Chr5:2067831-2089916 (-)
C3H/HeJ ENSMUSG00175006364
 protein coding gene Chr8:28954121-28955506 (-)
C3H/HeJ ENSMUSG00175026249
 protein coding gene Chr5:2217258-2239344 (-)
C57BL/6NJ ENSMUSG00215011454
 protein coding gene Chr5:2499171-2521257 (-)
C57BL/6NJ ENSMUSG00215005780
 protein coding gene Chr8:28747698-28750637 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026947
 protein coding gene Chr5:2422705-2444590 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210002665
 protein coding gene Chr5:2581835-2603920 (-)
DBA/2J ENSMUSG00185001823
 protein coding gene Chr8:34708631-34710016 (-)
DBA/2J ENSMUSG00185028928
 protein coding gene Chr5:2585607-2607692 (-)
FVB/NJ ENSMUSG00205006967
 protein coding gene Chr5:2295652-2317737 (-)
JF1/MsJ ENSUMUG00000002643
 protein coding gene Chr5:2624320-2646147 (-)
LP/J ENSMUSG00230002303
 protein coding gene Chr5:6501388-6523472 (-)
NOD/ShiLtJ ENSMUSG00190012296
 protein coding gene Chr5:2257350-2279176 (-)
NZO/HlLtJ ENSMUSG00225007792
 protein coding gene Chr5:10265955-10288039 (-)
NZO/HlLtJ ENSMUSG00225014792
 protein coding gene Chr8:41962334-41963544 (-)
PWK/PhJ ENSLUMG00010018579
 protein coding gene Chr5:2554826-2574973 (-)
SPRET/EiJ ENSMSPG00010004939
 protein coding gene Chr5:2433183-2453176 (-)
WSB/EiJ ENSIUOG00005026202
 protein coding gene Chr5:2283944-2306028 (-)



Homology
more
  • Human Ortholog
    GTPBP10, GTP binding protein 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTPBP10, GTP binding protein 10
  • Synonyms
    ObgH2, UG0751c10
  • Links
    NCBI Gene ID: 85865
    UniProt: A4D1E9

  • Chr Location
    7q21.13; chr7:90335223-90391453 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    613
  • Tissues
    16
  • cDNA Data
    9
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040464 Ensembl Gene Model | MGI Sequence Detail 22085 C57BL/6J ±  kb
    transcript ENSMUST00000115441 Ensembl | MGI Sequence Detail 2972 Not Applicable  
    polypeptide ENSMUSP00000111101 Ensembl | MGI Sequence Detail 366 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1922050
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:367686 Briere A, et al., Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies. Invest Ophthalmol Vis Sci. 2025 May 1;66(5):7
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory