Zfp958 Gene Detail

Summary

• Symbol
  Zfp958
• Name
  zinc finger protein 958
• Synonyms
  BC003267

• Feature Type
  protein coding gene
• IDs
  MGI:2385298
  NCBI Gene: 233987
• Alliance
  gene page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr8:4663167-4680231 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 2.07 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  39 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2385298	protein coding gene	Chr8:4663167-4682572 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0033336	protein coding gene	Chr8:1595909-1613962 (+)
A/J	MGP_AJ_G0033317	protein coding gene	Chr8:1532002-1548904 (+)
AKR/J	MGP_AKRJ_G0033248	protein coding gene	Chr8:1585426-1602569 (+)
BALB/cJ	MGP_BALBcJ_G0033317	protein coding gene	Chr8:1600168-1616467 (+)
C3H/HeJ	MGP_C3HHeJ_G0033031	protein coding gene	Chr8:1599659-1617127 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0033829	protein coding gene	Chr8:1648637-1671167 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030801	protein coding gene	Chr8:1414375-1428149 (+)
CAST/EiJ	MGP_CASTEiJ_G0032354	protein coding gene	Chr8:1452901-1470085 (+)
CBA/J	MGP_CBAJ_G0033004	protein coding gene	Chr8:1708261-1724146 (+)
DBA/2J	MGP_DBA2J_G0033158	protein coding gene	Chr8:1489471-1506455 (+)
FVB/NJ	MGP_FVBNJ_G0033105	protein coding gene	Chr8:1551455-1567209 (+)
LP/J	MGP_LPJ_G0033252	protein coding gene	Chr8:1508633-1526061 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0033140	protein coding gene	Chr8:1674467-1692441 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033846	protein coding gene	Chr8:1562600-1578116 (+)
PWK/PhJ	MGP_PWKPhJ_G0032066	protein coding gene	Chr8:1443761-1460228 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0031909	protein coding gene	Chr8:1449495-1464297 (+)
WSB/EiJ	MGP_WSBEiJ_G0032469	protein coding gene	Chr8:1545756-1562375 (+)

Homology

• Human Ortholog
  ZNF117, zinc finger protein 117

• Vertebrate Orthologs
  5

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  ZNF117, zinc finger protein 117
  
• Synonyms
  HPF9, H-plk
• Links
  HGNC:12897

  NCBI Gene ID: 51351

  neXtProt AC: NX_Q03924

  UniProt: Q03924

  
  
• Chr Location
  7q11.21; chr7:64971772-65006684 (-)  GRCh38

---

• Human Ortholog
  ZNF490, zinc finger protein 490
  
• Links
  HGNC:23705

  NCBI Gene ID: 57474

  neXtProt AC: NX_Q9ULM2

  UniProt: Q9ULM2

  
  
• Chr Location
  19p13.2-p13.13; chr19:12576100-12640098 (-)  GRCh38

---

• Human Ortholog
  ZNF708, zinc finger protein 708
  
• Synonyms
  KOX8, ZNF15, ZNF15L1
• Links
  HGNC:12945

  NCBI Gene ID: 7562

  neXtProt AC: NX_P17019

  UniProt: P17019

  
  
• Chr Location
  chr19:21291160-21329425 (-)  GRCh38

---

• Human Ortholog
  ZNF716, zinc finger protein 716
  
• Links
  HGNC:32458

  NCBI Gene ID: 441234

  neXtProt AC: NX_A6NP11

  UniProt: A6NP11

  
  
• Chr Location
  7p11.2; chr7:57450177-57473559 (+)  GRCh38

---

• MGI Vertebrate Homology
  Zfp958 stringent orthology
  4 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: ZNF117, ZNF490, ZNF708, ZNF716
• Gene Tree
  Zfp958
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  12
• Gene trapped
  12
• Incidental Mutations
  Mutagenetix , CvDC
• Find Mice (IMSR)
  29 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  6
• GO References
  1

Expression

• Assay Results
  709
• Tissues
  3
• cDNA Data
  8
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  37
• RefSeq
  6
• UniProt
  2
• CCDS
  CCDS80856.1

• Ensembl
  ENSMUSG00000058748 (Evidence)
• NCBI Gene
  233987

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000058748	Ensembl Gene Model | MGI Sequence Detail	17065	C57BL/6J
transcript	ENSMUST00000202692	Ensembl | MGI Sequence Detail	2364	Not Applicable
polypeptide	ENSMUSP00000143842	Ensembl | MGI Sequence Detail	467	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR036051 KRAB domain superfamily
  IPR001909 Krueppel-associated box
  IPR036236 Zinc finger C2H2 superfamily
  IPR013087 Zinc finger C2H2-type

Molecular
Reagents

• All nucleic 9

  Genomic 1

  cDNA 8

  
  

  Microarray probesets 2

References

• Summaries
  All 21

  Developmental Gene Expression 1

  Gene Ontology 1

  Phenotypes 4
• Earliest
  J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
• Latest
  J:156017 Yokoyama S, et al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48

TSS for Zfp958:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr76134	Chr8:4663131-4663142 (+)	-30 bp
Tssr76135	Chr8:4663152-4663177 (+)	-2 bp
Tssr76136	Chr8:4663182-4663207 (+)	28 bp
Tssr76137	Chr8:4663211-4663224 (+)	51 bp