Ubtd1 Gene Detail

Summary

• Symbol
  Ubtd1
• Name
  ubiquitin domain containing 1
• Synonyms
  MGC:28905

• Feature Type
  protein coding gene
• IDs
  MGI:2385092
  NCBI Gene: 226122
• Alliance
  genome feature page
• Transcription Start Sites
  10 TSS

Location &
Maps

• Sequence Map
  Chr19:41970202-42023082 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, 35.56 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  1380 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2385092	protein coding gene	Chr19:41970202-42023089 (+)
129S1/SvImJ	ENSMUSG00200026207	protein coding gene	Chr19:38702228-38757825 (+)
A/J	ENSMUSG00195010264	protein coding gene	Chr19:38806965-38862535 (+)
AKR/J	ENSMUSG00220018140	protein coding gene	Chr19:38619023-38674619 (+)
BALB/cJ	ENSMUSG00180028570	protein coding gene	Chr19:39059377-39114951 (+)
C3H/HeJ	ENSMUSG00175038688	protein coding gene	Chr19:38581225-38636815 (+)
C57BL/6NJ	ENSMUSG00215024542	protein coding gene	Chr19:38659706-38712590 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022962	protein coding gene	Chr19:38655920-38711374 (+)
CAST/EiJ	ENSTCUG00005013618	protein coding gene	Chr19:38264915-38320428 (+)
CBA/J	ENSMUSG00210031837	protein coding gene	Chr19:38663344-38718936 (+)
DBA/2J	ENSMUSG00185032477	protein coding gene	Chr19:39183526-39239118 (+)
FVB/NJ	ENSMUSG00205006542	protein coding gene	Chr19:38134066-38189655 (+)
JF1/MsJ	ENSUMUG00000044481	protein coding gene	Chr19:39347259-39402622 (+)
LP/J	ENSMUSG00230034273	protein coding gene	Chr19:39972325-40027917 (+)
NOD/ShiLtJ	ENSMUSG00190011084	protein coding gene	Chr19:38533337-38588933 (+)
NZO/HlLtJ	ENSMUSG00225041806	protein coding gene	Chr19:43530352-43586167 (+)
PWK/PhJ	ENSLUMG00010000815	protein coding gene	Chr19:38516362-38571742 (+)
SPRET/EiJ	ENSMSPG00010019310	protein coding gene	Chr19:38248192-38304849 (+)
WSB/EiJ	ENSIUOG00005036683	protein coding gene	Chr19:38039955-38095570 (+)

Homology

• Human Ortholog
  UBTD1, ubiquitin domain containing 1

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  UBTD1, ubiquitin domain containing 1
  
• Links
  HGNC:25683

  NCBI Gene ID: 80019

  UniProt: Q9HAC8

  
  
• Chr Location
  10q24.1-q24.2; chr10:97498913-97571206 (+)  GRCh38

---

• MGI Vertebrate Homology
  Ubtd1 stringent orthology
  1 human;1 mouse;1 rat;2 zebrafish
  
• HCOP
  vertebrate homology predictions: UBTD1
• Gene Tree
  Ubtd1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  35
• Endonuclease-mediated
  1
• Gene trapped
  32
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  20 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  597
• cDNA Data
  32

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase ubtd1
  ZFIN ubtd1b

Sequences &
Gene Models

• All Sequences
  37
• RefSeq
  6
• UniProt
  1
• CCDS
  CCDS29819.1

• Ensembl
  ENSMUSG00000025171 (Evidence)
• NCBI Gene
  226122

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000025171	Ensembl Gene Model | MGI Sequence Detail	52881	C57BL/6J
transcript	ENSMUST00000026170	Ensembl | MGI Sequence Detail	1529	Not Applicable
polypeptide	ENSMUSP00000026170	Ensembl | MGI Sequence Detail	227	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000031330 ubiquitin domain-containing protein 1
  (term hierarchy)
• InterPro Domains
  IPR032752 DC-UbP/UBTD2, N-terminal domain
  IPR038169 DC-UbP/UBTD2, N-terminal domain superfamily
  IPR019956 Ubiquitin domain
  IPR039869 Ubiquitin domain-containing protein 1/2
  IPR000626 Ubiquitin-like domain
  IPR029071 Ubiquitin-like domain superfamily
• GlyGen
  Q91WB7 1 site

Molecular
Reagents

• All nucleic 32

  cDNA 32

  
  

  Microarray probesets 4

References

• Summaries
  All 29

  Phenotypes 8
• Earliest
  J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
• Latest
  J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ubtd1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr156451	Chr19:41969666-41969685 (+)	-526 bp
Tssr156452	Chr19:41969694-41969722 (+)	-494 bp
Tssr156453	Chr19:41969762-41969788 (+)	-427 bp
Tssr156454	Chr19:41969909-41969920 (+)	-287 bp
Tssr156455	Chr19:41970062-41970077 (+)	-132 bp
Tssr156456	Chr19:41970100-41970145 (+)	-79 bp
Tssr156457	Chr19:41970148-41970217 (+)	-19 bp
Tssr5517	Chr19:41970226-41970237 (+)	30 bp
Tssr156458	Chr19:42007829-42007850 (+)	37,638 bp
Tssr156459	Chr19:42010638-42010656 (+)	40,445 bp