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Rhbdl1 Gene Detail
Summary
  • Symbol
    Rhbdl1
  • Name
    rhomboid like 1
  • Synonyms
    MGC:28800, Rhbdl
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384891
    NCBI Gene: 214951
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26053439-26056101 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.93 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    67 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384891
 protein coding gene Chr17:26053439-26056269 (-)
129S1/SvImJ ENSMUSG00200049531
 protein coding gene Chr17:21498432-21501262 (-)
A/J ENSMUSG00195048201
 protein coding gene Chr17:22515626-22518455 (-)
AKR/J ENSMUSG00220053216
 protein coding gene Chr17:21562381-21565212 (-)
BALB/cJ ENSMUSG00180047231
 protein coding gene Chr17:21796438-21799268 (-)
C3H/HeJ ENSMUSG00175053659
 protein coding gene Chr17:21554683-21557512 (-)
C57BL/6NJ ENSMUSG00215053027
 protein coding gene Chr17:21563024-21565854 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021257
 protein coding gene Chr17:21668915-21671741 (-)
CAST/EiJ ENSTCUG00005047020
 protein coding gene Chr17:22144525-22147352 (-)
CBA/J ENSMUSG00210049272
 protein coding gene Chr17:21393524-21396353 (-)
DBA/2J ENSMUSG00185040637
 protein coding gene Chr17:23603891-23606719 (-)
FVB/NJ ENSMUSG00205036928
 protein coding gene Chr17:21859345-21862174 (-)
JF1/MsJ ENSUMUG00000055600
 protein coding gene Chr17:23059197-23062025 (-)
LP/J ENSMUSG00230054499
 protein coding gene Chr17:25002967-25005797 (-)
NOD/ShiLtJ ENSMUSG00190054079
 protein coding gene Chr17:21492606-21495434 (-)
NZO/HlLtJ ENSMUSG00225052800
 protein coding gene Chr17:26922957-26925784 (-)
PWK/PhJ ENSLUMG00010039012
 protein coding gene Chr17:20978328-20981160 (-)
SPRET/EiJ ENSMSPG00010047286
 protein coding gene Chr17:22297210-22300040 (-)
WSB/EiJ ENSIUOG00005046582
 protein coding gene Chr17:22236271-22239099 (-)



Homology
more
  • Human Ortholog
    RHBDL1, rhomboid like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RHBDL1, rhomboid like 1
  • Synonyms
    RHBDL, RRP
  • Links
    NCBI Gene ID: 9028
    UniProt: O75783

  • Chr Location
    16p13.3; chr16:675671-678268 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    9
  • cDNA Data
    6
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 214951 NCBI Gene Model | MGI Sequence Detail 2663 C57BL/6J ±  kb
    transcript NM_144816 RefSeq | MGI Sequence Detail 1572 C57BL/6  
    polypeptide Q8VC82 UniProt | EBI | MGI Sequence Detail 373 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 3
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:86784 Bergstrom DE, et al., Overlapping deletions spanning the proximal two-thirds of the mouse t complex. Mamm Genome. 2003 Dec;14(12):817-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory