Mthfr-ps1 Pseudogene Detail

Summary

• Symbol
  Mthfr-ps1
• Name
  5,10-methylenetetrahydrofolate reductase, pseudogene 1

• Feature Type
  pseudogene
• IDs
  MGI:2384077
  NCBI Gene: 387594
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr5:78621732-78622582 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 42.22 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  84 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2384077	pseudogene	Chr5:78621722-78622981 (+)
129S1/SvImJ	ENSMUSG00200001455	pseudogene	Chr5:74335279-74336144 (+)
A/J	ENSMUSG00195010765	pseudogene	Chr5:73510910-73511760 (+)
AKR/J	ENSMUSG00220014917	pseudogene	Chr5:73631362-73632225 (+)
BALB/cJ	ENSMUSG00180000087	pseudogene	Chr5:73389215-73390066 (+)
C3H/HeJ	ENSMUSG00175004254	pseudogene	Chr5:75416371-75417234 (+)
C57BL/6NJ	ENSMUSG00215000477	pseudogene	Chr5:74210117-74210967 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0011473	pseudogene	Chr4:137881248-137883677 (+)
CAST/EiJ	ENSTCUG00005013832	pseudogene	Chr5:73097911-73098776 (+)
CBA/J	ENSMUSG00210000694	pseudogene	Chr5:74240707-74241570 (+)
DBA/2J	ENSMUSG00185016574	pseudogene	Chr5:76184245-76185108 (+)
FVB/NJ	ENSMUSG00205001145	pseudogene	Chr5:73136618-73137481 (+)
JF1/MsJ	ENSUMUG00000006829	pseudogene	Chr5:80614902-80615767 (+)
LP/J	ENSMUSG00230022911	pseudogene	Chr5:80893243-80894107 (+)
NOD/ShiLtJ	ENSMUSG00190007690	pseudogene	Chr5:73218840-73219703 (+)
NZO/HlLtJ	ENSMUSG00225034720	pseudogene	Chr5:85940343-85941208 (+)
PWK/PhJ	ENSLUMG00010007664	pseudogene	Chr5:73098281-73099145 (+)
SPRET/EiJ	ENSMSPG00010010206	pseudogene	Chr5:75085013-75085407 (+)
WSB/EiJ	ENSIUOG00005018370	pseudogene	Chr5:76120274-76120939 (+)

Homology

• Gene Tree
  Mthfr-ps1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  2
• Spontaneous
  1
• Genomic Mutations
  3 involving Mthfr-ps1
• Find Mice (IMSR)
  3 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  1

• Ensembl
  ENSMUSG00000044058 (Evidence)
• NCBI Gene
  387594

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000044058	Ensembl Gene Model | MGI Sequence Detail	851	C57BL/6J
transcript	ENSMUST00000174153	Ensembl | MGI Sequence Detail	601	Not Applicable

References

• Summaries
  All 9

  Phenotypes 4
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:86338 Leclerc D, et al., Characterization of a pseudogene for murine methylenetetrahydrofolate reductase. Mol Cell Biochem. 2003 Oct;252(1-2):391-5