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Serpina3h Pseudogene Detail
Summary
  • Symbol
    Serpina3h
  • Name
    serine (or cysteine) peptidase inhibitor, clade A, member 3H
  • Synonyms
    6C28, alpha-1 antiproteinase
  • Feature Type
    pseudogene
  • IDs
    MGI:2182839
    NCBI Gene: 546546
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr12:104216411-104219928 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 53.74 cM, cytoband F1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2182839
 pseudogene Chr12:104214155-104220664 (+)
129S1/SvImJ MGP_129S1SvImJ_G0039795
 pseudogene Chr12:106011052-106018204 (+)
A/J MGP_AJ_G0039794
 pseudogene Chr12:102012013-102015544 (+)
AKR/J MGP_AKRJ_G0039721
 pseudogene Chr12:104894411-104900850 (+)
BALB/cJ MGP_BALBcJ_G0039768
 pseudogene Chr12:102355900-102360641 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0040331
 pseudogene Chr12:109328485-109334287 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0038539
 pseudogene Chr12:100188250-100216359 (+)
CBA/J MGP_CBAJ_G0039396
 pseudogene Chr12:113380911-113411394 (+)
DBA/2J MGP_DBA2J_G0039594
 pseudogene Chr12:101487634-101489844 (+)
FVB/NJ MGP_FVBNJ_G0039551
 pseudogene Chr12:100275193-100311841 (+)
LP/J MGP_LPJ_G0039629
 pseudogene Chr12:105849884-105855648 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0039552
 pseudogene Chr12:116970504-116991961 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0040433
 pseudogene Chr12:104377678-104383442 (+)
PWK/PhJ MGP_PWKPhJ_G0038218
 pseudogene Chr12:95934517-95937374 (-)
SPRET/EiJ MGP_SPRETEiJ_G0037960
 pseudogene Chr12:98585357-98619911 (+)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041449 Ensembl Gene Model | MGI Sequence Detail 3518 C57BL/6J ±  kb
transcript ENSMUST00000116393 Ensembl | MGI Sequence Detail 1226 Not Applicable  
polypeptide Q3U1B7 UniProt | EBI | MGI Sequence Detail 409 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6
References
more
  • Summaries
    All 14
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:25107 Inglis JD, et al., The murine Spi-2 proteinase inhibitor locus: a multigene family with a hypervariable reactive site domain. EMBO J. 1991 Feb;10(2):255-61
  • Latest
    J:97996 Winkler IG, et al., Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization. J Exp Med. 2005 Apr 4;201(7):1077-88
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory