Jpx Gene Detail

Summary

• Symbol
  Jpx
• Name
  Jpx transcript, Xist activator (non-protein coding)
• Synonyms
  2010000I03Rik, 2510040I06Rik, Enox

• Feature Type
  lncRNA gene
• IDs
  MGI:2180008
  NCBI Gene: 70252
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  ChrX:102537164-102550031 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, 46.17 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  342 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2180008	lncRNA gene	ChrX:102536977-102609302 (+)
129S1/SvImJ	ENSMUSG00200039618	lncRNA gene	ChrX:84302281-84374625 (+)
A/J	ENSMUSG00195043421	lncRNA gene	ChrX:88057012-88129359 (+)
AKR/J	ENSMUSG00220040887	lncRNA gene	ChrX:82724665-82796811 (+)
BALB/cJ	ENSMUSG00180043537	lncRNA gene	ChrX:84734282-84806635 (+)
C3H/HeJ	ENSMUSG00175046004	lncRNA gene	ChrX:88307125-88379451 (+)
C57BL/6NJ	ENSMUSG00215046948	lncRNA gene	ChrX:84914205-84986365 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006878	lincRNA gene	ChrX:97715295-97728452 (+)
CAST/EiJ	ENSTCUG00005043972	lncRNA gene	ChrX:85777677-85849680 (+)
CBA/J	ENSMUSG00210046685	lncRNA gene	ChrX:85197951-85270285 (+)
DBA/2J	ENSMUSG00185043963	lncRNA gene	ChrX:97637153-97709273 (+)
FVB/NJ	ENSMUSG00205034472	lncRNA gene	ChrX:84279408-84351758 (+)
JF1/MsJ	ENSUMUG00000041243	lncRNA gene	ChrX:118244999-118316810 (+)
LP/J	ENSMUSG00230042700	lncRNA gene	ChrX:104335466-104407797 (+)
NOD/ShiLtJ	ENSMUSG00190043234	lncRNA gene	ChrX:84355763-84428106 (+)
NZO/HlLtJ	ENSMUSG00225045936	lncRNA gene	ChrX:109455764-109527946 (+)
PWK/PhJ	ENSLUMG00010039014	lncRNA gene	ChrX:83559621-83631619 (+)
SPRET/EiJ	ENSMSPG00010043020	lncRNA gene	ChrX:87763921-87836036 (+)
WSB/EiJ	ENSIUOG00005045731	lncRNA gene	ChrX:84859223-84931404 (+)

Homology

• Human Ortholog
  JPX, JPX transcript, XIST activator

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  JPX, JPX transcript, XIST activator
  
• Synonyms
  DCBALD06, ENOX, LINC00183, NCRNA00183
• Links
  HGNC:37191

  NCBI Gene ID: 554203

  
  
• Chr Location
  Xq13.2; chrX:73943934-74070423 (+)  GRCh38

---

• MGI Vertebrate Homology
  Jpx stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: JPX
• Gene Tree
  Jpx
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  4
• Endonuclease-mediated
  4
• Genomic Mutations
  1 involving Jpx
• Find Mice (IMSR)
  2 strains or lines available

Heterozygous knockout does not affect transmission of the maternal mutated allele.

Expression

• Assay Results
  597
• cDNA Data
  7

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  135
• RefSeq
  1

• Ensembl
  ENSMUSG00000097571 (Evidence)
• NCBI Gene
  70252

Representative Sequences			Length	Strain/Species
genomic	70252	NCBI Gene Model | MGI Sequence Detail	12868	C57BL/6J
transcript	NR_015508	RefSeq | MGI Sequence Detail	3802	ZRU/MplStud

Molecular
Reagents

• All nucleic 8

  cDNA 8

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:1917502, MGI:1923836

References

• Summaries
  All 27

  Phenotypes 2
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:380795 Luo H, et al., Photocatalytic Chemical Crosslinking for Profiling RNA-Protein Interactions in Living Cells. Angew Chem Int Ed Engl. 2022 Jul 4;61(27):e202202008

TSS for Jpx:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr161728	ChrX:102537375-102537388 (+)	218 bp