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Stab1 Gene Detail
Summary
  • Symbol
    Stab1
  • Name
    stabilin 1
  • Synonyms
    mKIAA0246, MS-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2178742
    NCBI Gene: 192187
  • Alliance
    genome feature page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30860970-30890598 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 19.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    745 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2178742
 protein coding gene Chr14:30860970-30890616 (-)
129S1/SvImJ ENSMUSG00200036868
 protein coding gene Chr14:22682594-22712222 (-)
A/J ENSMUSG00195013513
 protein coding gene Chr14:23758203-23787831 (-)
AKR/J ENSMUSG00220031764
 protein coding gene Chr14:22870589-22900217 (-)
BALB/cJ ENSMUSG00180023634
 protein coding gene Chr14:22846783-22876411 (-)
C3H/HeJ ENSMUSG00175039897
 protein coding gene Chr14:22914089-22943717 (-)
C57BL/6NJ ENSMUSG00215027632
 protein coding gene Chr14:23152486-23182115 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019067
 protein coding gene Chr14:23455926-23486176 (-)
CAST/EiJ ENSTCUG00005022826
 protein coding gene Chr14:23002280-23031894 (-)
CBA/J ENSMUSG00210038458
 protein coding gene Chr14:23156989-23186617 (-)
DBA/2J ENSMUSG00185036266
 protein coding gene Chr14:27426355-27455983 (-)
FVB/NJ ENSMUSG00205021505
 protein coding gene Chr14:23016095-23045723 (-)
JF1/MsJ ENSUMUG00000036960
 protein coding gene Chr14:34685329-34714876 (-)
LP/J ENSMUSG00230032894
 protein coding gene Chr14:34706602-34736230 (-)
NOD/ShiLtJ ENSMUSG00190016310
 protein coding gene Chr14:23170606-23200234 (-)
NZO/HlLtJ ENSMUSG00225035996
 protein coding gene Chr14:29045294-29074922 (-)
PWK/PhJ ENSLUMG00010020610
 protein coding gene Chr14:11280639-11310198 (-)
SPRET/EiJ ENSMSPG00010039497
 protein coding gene Chr14:24823485-24853029 (-)
WSB/EiJ ENSIUOG00005011866
 protein coding gene Chr14:22975137-23004969 (-)



Homology
more
  • Human Ortholog
    STAB1, stabilin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STAB1, stabilin 1
  • Synonyms
    CLEVER-1, FEEL-1, FEEL1, FELE-1, FEX1, HRFT, SCARH2, STAB-1
  • Links
    NCBI Gene ID: 23166
    UniProt: Q9NY15

  • Chr Location
    3p21.1; chr3:52495337-52524512 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 2 genetic backgrounds
    12 phenotypes from multigenic genotypes
    2 images
    25 phenotype references
Mice homozygous for a knock-out allele exhibit no physical or behavioral abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    701
  • Tissues
    64
  • cDNA Data
    74
  • Literature Summary
    10
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042286 Ensembl Gene Model | MGI Sequence Detail 29629 C57BL/6J ±  kb
transcript ENSMUST00000036618 Ensembl | MGI Sequence Detail 7999 Not Applicable  
polypeptide ENSMUSP00000046199 Ensembl | MGI Sequence Detail 2571 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    cDNA 75
    Primer pair 3

    Microarray probesets 4
References
more
  • Summaries
    All 69
    Developmental Gene Expression 10
    Gene Ontology 7
    Phenotypes 25
  • Earliest
    J:75013 Politz O, et al., Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues. Biochem J. 2002 Feb 15;362(Pt 1):155-64
  • Latest
    J:354240 Krzistetzko J, et al., Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice. Int J Mol Sci. 2023 Jun 30;24(13)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory