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Or2b4 Gene Detail
Summary
  • Symbol
    Or2b4
  • Name
    olfactory receptor family 2 subfamily B member 4
  • Synonyms
    A3, GA_x6K02T2PSCP-2264806-2265753, MOR256-3, Olfr124, SR1
Location &
Maps
more
  • Sequence Map
    Chr17:38115960-38117081 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2177507
 protein coding gene Chr17:38110779-38119508 (+)
129S1/SvImJ ENSMUSG00200046177
 protein coding gene Chr17:33612761-33621491 (+)
A/J ENSMUSG00195042339
 protein coding gene Chr17:34775361-34784090 (+)
AKR/J ENSMUSG00220036745
 protein coding gene Chr17:33545037-33553766 (+)
BALB/cJ ENSMUSG00180030087
 protein coding gene Chr17:34302101-34303222 (+)
C3H/HeJ ENSMUSG00175040178
 protein coding gene Chr17:33490649-33491770 (+)
C57BL/6NJ ENSMUSG00215051263
 protein coding gene Chr17:33409194-33417923 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021594
 protein coding gene Chr17:34733699-34734828 (+)
CAST/EiJ ENSTCUG00005049498
 protein coding gene Chr17:34625086-34633815 (+)
CBA/J ENSMUSG00210043302
 protein coding gene Chr17:33221695-33230424 (+)
DBA/2J ENSMUSG00185052502
 protein coding gene Chr17:36282981-36284102 (+)
FVB/NJ ENSMUSG00205033071
 protein coding gene Chr17:33801339-33811747 (+)
JF1/MsJ ENSUMUG00000045855
 protein coding gene Chr17:35199844-35208573 (+)
LP/J ENSMUSG00230054291
 protein coding gene Chr17:37407988-37416718 (+)
NOD/ShiLtJ ENSMUSG00190052935
 protein coding gene Chr17:33450537-33459266 (+)
NZO/HlLtJ ENSMUSG00225054877
 protein coding gene Chr17:39366187-39374916 (+)
PWK/PhJ ENSLUMG00010031375
 protein coding gene Chr17:33091382-33100110 (+)
SPRET/EiJ ENSMSPG00010030884
 protein coding gene Chr17:34385087-34389106 (+)
WSB/EiJ ENSIUOG00005046755
 protein coding gene Chr17:34335554-34336675 (+)



Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 5 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit a significantly reduced density of olfactory sensory neurons in the septal organ, and show altered patterns of odorant responses.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    672
  • Tissues
    21
  • cDNA Data
    5
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 259064 NCBI Gene Model | MGI Sequence Detail 1122 C57BL/6J ±  kb
transcript NM_147062 RefSeq | MGI Sequence Detail 1122 Not Specified  
polypeptide NP_667273 RefSeq | MGI Sequence Detail 315 Not Specified  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
    IPR000725 Olfactory receptor
Molecular
Reagents
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  • All nucleic 10
    Genomic 1
    cDNA 5
    Primer pair 2
    Other 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:7276512
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:74521 Zhang X, et al., The olfactory receptor gene superfamily of the mouse. Nat Neurosci. 2002 Feb;5(2):124-33
  • Latest
    J:389356 Ukhanov K, et al., Constancy of olfactory cilia in rodents. Chem Senses. 2025 Jan 22;50
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory