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Wdr18 Gene Detail
Summary
  • Symbol
    Wdr18
  • Name
    WD repeat domain 18
  • Synonyms
    2310012I10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2158400
    NCBI Gene: 216156
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79795989-79805081 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    231 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2158400
 protein coding gene Chr10:79795986-79806037 (+)
129S1/SvImJ ENSMUSG00200041095
 protein coding gene Chr10:76419654-76429705 (+)
A/J ENSMUSG00195039331
 protein coding gene Chr10:76815165-76825216 (+)
AKR/J ENSMUSG00220045611
 protein coding gene Chr10:76412724-76422775 (+)
BALB/cJ ENSMUSG00180049234
 protein coding gene Chr10:76825665-76835716 (+)
C3H/HeJ ENSMUSG00175052014
 protein coding gene Chr10:76696382-76706433 (+)
C57BL/6NJ ENSMUSG00215048605
 protein coding gene Chr10:76438070-76448121 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015555
 protein coding gene Chr10:73941728-73950966 (+)
CAST/EiJ ENSTCUG00005048132
 protein coding gene Chr10:76322811-76332906 (+)
CBA/J ENSMUSG00210036742
 protein coding gene Chr10:76552452-76562503 (+)
DBA/2J ENSMUSG00185049805
 protein coding gene Chr10:76894844-76904895 (+)
FVB/NJ ENSMUSG00205033290
 protein coding gene Chr10:76607625-76617676 (+)
JF1/MsJ ENSUMUG00000047261
 protein coding gene Chr10:78125317-78135396 (+)
LP/J ENSMUSG00230049043
 protein coding gene Chr10:78664577-78674628 (+)
NOD/ShiLtJ ENSMUSG00190030343
 protein coding gene Chr10:76808578-76818629 (+)
NZO/HlLtJ ENSMUSG00225050075
 protein coding gene Chr10:82950930-82960981 (+)
PWK/PhJ ENSLUMG00010040386
 protein coding gene Chr10:76484717-76494798 (+)
SPRET/EiJ ENSMSPG00010038181
 protein coding gene Chr10:78105192-78115506 (+)
WSB/EiJ ENSIUOG00005050616
 protein coding gene Chr10:76513054-76523052 (+)



Homology
more
  • Human Ortholog
    WDR18, WD repeat domain 18
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR18, WD repeat domain 18
  • Synonyms
    Ipi3, R32184_1
  • Links
    NCBI Gene ID: 57418
    UniProt: Q9BV38

  • Chr Location
    19p13.3; chr19:982928-998438 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    123
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 216156 NCBI Gene Model | MGI Sequence Detail 9093 C57BL/6J ±  kb
transcript NR_184850 RefSeq | MGI Sequence Detail 2975 C57BL/6  
polypeptide Q4VBE8 UniProt | EBI | MGI Sequence Detail 431 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 125
    Genomic 1
    cDNA 123
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923697, MGI:2143769, MGI:2143813
References
more
  • Summaries
    All 50
    Gene Ontology 6
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:363654 Wang J, et al., Cortex-Specific Tmem169 Deficiency Induces Defects in Cortical Neuron Development and Autism-Like Behaviors in Mice. J Neurosci. 2025 Feb 26;45(9)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory